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Substrate-induced assembly and functional mechanism of the membrane protein insertase SecYEG-YidC.

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Title: Substrate-induced assembly and functional mechanism of the membrane protein insertase SecYEG-YidC.
Authors: Busch M; Synthetic Membrane Systems, Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany., Rosales-Hernandez C; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany.; Max Planck Institute of Biophysics, Frankfurt/Main, Germany., Kamel M; Synthetic Membrane Systems, Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany.; Dept. Biology, Osnabrück University, Osnabrück, Germany., Schaumkessel Y; Synthetic Membrane Systems, Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany.; Institute of Biochemistry and Molecular Biology I, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., van der Sluis EO; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany.; Kavli Institute of Nanosciences, Delft University of Technology, Delft, the Netherlands., Berninghausen O; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany., Becker T; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany., Beckmann R; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany. Beckmann@genzentrum.lmu.de., Kedrov A; Synthetic Membrane Systems, Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany. Kedrov@hhu.de.; Interfaculty Center for Membrane Research, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany. Kedrov@hhu.de.
Source: The EMBO journal [EMBO J] 2026 Jun 26. Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Substrate-induced assembly and functional mechanism of the membrane protein insertase SecYEG-YidC.
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  Data: <searchLink fieldCode="AU" term="%22Busch+M%22">Busch M</searchLink>; Synthetic Membrane Systems, Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany.<br /><searchLink fieldCode="AU" term="%22Rosales-Hernandez+C%22">Rosales-Hernandez C</searchLink>; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany.; Max Planck Institute of Biophysics, Frankfurt/Main, Germany.<br /><searchLink fieldCode="AU" term="%22Kamel+M%22">Kamel M</searchLink>; Synthetic Membrane Systems, Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany.; Dept. Biology, Osnabrück University, Osnabrück, Germany.<br /><searchLink fieldCode="AU" term="%22Schaumkessel+Y%22">Schaumkessel Y</searchLink>; Synthetic Membrane Systems, Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany.; Institute of Biochemistry and Molecular Biology I, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22van+der+Sluis+EO%22">van der Sluis EO</searchLink>; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany.; Kavli Institute of Nanosciences, Delft University of Technology, Delft, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Berninghausen+O%22">Berninghausen O</searchLink>; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+T%22">Becker T</searchLink>; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany.<br /><searchLink fieldCode="AU" term="%22Beckmann+R%22">Beckmann R</searchLink>; Gene Center Munich, Ludwig Maximilian University Munich, Munich, 81377, Germany. Beckmann@genzentrum.lmu.de.<br /><searchLink fieldCode="AU" term="%22Kedrov+A%22">Kedrov A</searchLink>; Synthetic Membrane Systems, Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany. Kedrov@hhu.de.; Interfaculty Center for Membrane Research, Heinrich Heine University Düsseldorf, Düsseldorf, 40225, Germany. Kedrov@hhu.de.
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        Value: 10.1038/s44318-026-00837-6
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              Text: 2026 Jun 26
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