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Intranasal boosting induces variant-specific responses in SARS-CoV-2 vaccine-imprinted mice.

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Title: Intranasal boosting induces variant-specific responses in SARS-CoV-2 vaccine-imprinted mice.
Authors: Liang CY; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Scheaffer SM; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Case JB; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.; National Emerging Infectious Diseases Laboratories Department of Virology, Immunology, and Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Dmitriev IP; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA., Li Y; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Malladi SK; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA., Liu X; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Ying B; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Desai P; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.; Department of Microbial Pathogenesis and Immunology, Texas A&M University College of Medicine, Bryan, TX, USA., Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Curiel DT; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA., Ellebedy AH; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO, USA., Diamond MS; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.
Source: Nature communications [Nat Commun] 2026 Jun 27. Date of Electronic Publication: 2026 Jun 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Intranasal boosting induces variant-specific responses in SARS-CoV-2 vaccine-imprinted mice.
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  Data: <searchLink fieldCode="AU" term="%22Liang+CY%22">Liang CY</searchLink>; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Scheaffer+SM%22">Scheaffer SM</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Case+JB%22">Case JB</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.; National Emerging Infectious Diseases Laboratories Department of Virology, Immunology, and Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dmitriev+IP%22">Dmitriev IP</searchLink>; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Malladi+SK%22">Malladi SK</searchLink>; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Ying+B%22">Ying B</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Desai+P%22">Desai P</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.; Department of Microbial Pathogenesis and Immunology, Texas A&M University College of Medicine, Bryan, TX, USA.<br /><searchLink fieldCode="AU" term="%22Whelan+SPJ%22">Whelan SPJ</searchLink>; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Curiel+DT%22">Curiel DT</searchLink>; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Ellebedy+AH%22">Ellebedy AH</searchLink>; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Diamond+MS%22">Diamond MS</searchLink>; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO, USA. mdiamond@wustl.edu.
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