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Causality analysis of toxicological mechanisms in networked systems such as adverse outcome pathway networks.

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Title: Causality analysis of toxicological mechanisms in networked systems such as adverse outcome pathway networks.
Authors: Hartung T; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health and Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA. Thomas.Hartung@uni-konstanz.de.; CAAT-Europe, University of Konstanz, Konstanz, Germany. Thomas.Hartung@uni-konstanz.de.; Doerenkamp-Zbinden Chair for Evidence-Based Toxicology, Baltimore, MD, USA. Thomas.Hartung@uni-konstanz.de.; CAATevents, Solingen, Germany. Thomas.Hartung@uni-konstanz.de., Kopańska K; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health and Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA., Maertens A; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health and Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA., Whaley P; Evidence-Based Toxicology Collaboration, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Lancaster Environment Centre, Lancaster University, Lancaster, UK., Hoffmann S; Evidence-Based Toxicology Collaboration, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Seh Consulting + Services, Paderborn, Germany.
Source: Archives of toxicology [Arch Toxicol] 2026 Jun 27. Date of Electronic Publication: 2026 Jun 27.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hartung+T%22">Hartung T</searchLink>; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health and Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA. Thomas.Hartung@uni-konstanz.de.; CAAT-Europe, University of Konstanz, Konstanz, Germany. Thomas.Hartung@uni-konstanz.de.; Doerenkamp-Zbinden Chair for Evidence-Based Toxicology, Baltimore, MD, USA. Thomas.Hartung@uni-konstanz.de.; CAATevents, Solingen, Germany. Thomas.Hartung@uni-konstanz.de.<br /><searchLink fieldCode="AU" term="%22Kopańska+K%22">Kopańska K</searchLink>; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health and Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Maertens+A%22">Maertens A</searchLink>; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health and Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Whaley+P%22">Whaley P</searchLink>; Evidence-Based Toxicology Collaboration, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Lancaster Environment Centre, Lancaster University, Lancaster, UK.<br /><searchLink fieldCode="AU" term="%22Hoffmann+S%22">Hoffmann S</searchLink>; Evidence-Based Toxicology Collaboration, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Seh Consulting + Services, Paderborn, Germany.
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        Value: 10.1007/s00204-026-04386-z
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            – D: 27
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              Text: 2026 Jun 27
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