Structure-based immunopharmacological design of a multi-epitope vaccine candidate against Naegleria fowleri targeting TLR3: a pan-genomic and molecular dynamics approach.

Saved in:
Bibliographic Details
Title: Structure-based immunopharmacological design of a multi-epitope vaccine candidate against Naegleria fowleri targeting TLR3: a pan-genomic and molecular dynamics approach.
Authors: Faizan R; Department of Pharmacology and Clinical Therapeutics, School of Medicine, University of Malaga, Malaga, 29010, Spain., Naveed M; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54000, Pakistan. dr.naveed@ucp.edu.pk., Estevez IB; Department of Pharmacology and Clinical Therapeutics, School of Medicine, University of Malaga, Malaga, 29010, Spain., Rehman HM; School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan., Latif A; School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan., Hammad HM; National Centre for Bioinformatics, Quaid-I-Azam University Islamabad, Islamabad, Pakistan., Khan AR; Sindh Institute of Urology and Transplantation, Karachi, Pakistan., Alsulami SO; Department of Biochemistry, Faculty of Sciences, University of Tabuk, Tabuk, 71491, Saudi Arabia., Aljumaa MA; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia., Tombozara N; Institut Malgache de Recherches Appliquées (IMRA), Fondation Albert Et Suzanne Rakoto-Ratsimamanga, Avarabohitra Itaosy, PO Box 3833, Antananarivo, Madagascar. nzara89@gmail.com.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Jun 28. Date of Electronic Publication: 2026 Jun 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42365117
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Structure-based immunopharmacological design of a multi-epitope vaccine candidate against Naegleria fowleri targeting TLR3: a pan-genomic and molecular dynamics approach.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Faizan+R%22">Faizan R</searchLink>; Department of Pharmacology and Clinical Therapeutics, School of Medicine, University of Malaga, Malaga, 29010, Spain.<br /><searchLink fieldCode="AU" term="%22Naveed+M%22">Naveed M</searchLink>; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54000, Pakistan. dr.naveed@ucp.edu.pk.<br /><searchLink fieldCode="AU" term="%22Estevez+IB%22">Estevez IB</searchLink>; Department of Pharmacology and Clinical Therapeutics, School of Medicine, University of Malaga, Malaga, 29010, Spain.<br /><searchLink fieldCode="AU" term="%22Rehman+HM%22">Rehman HM</searchLink>; School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan.<br /><searchLink fieldCode="AU" term="%22Latif+A%22">Latif A</searchLink>; School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan.<br /><searchLink fieldCode="AU" term="%22Hammad+HM%22">Hammad HM</searchLink>; National Centre for Bioinformatics, Quaid-I-Azam University Islamabad, Islamabad, Pakistan.<br /><searchLink fieldCode="AU" term="%22Khan+AR%22">Khan AR</searchLink>; Sindh Institute of Urology and Transplantation, Karachi, Pakistan.<br /><searchLink fieldCode="AU" term="%22Alsulami+SO%22">Alsulami SO</searchLink>; Department of Biochemistry, Faculty of Sciences, University of Tabuk, Tabuk, 71491, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aljumaa+MA%22">Aljumaa MA</searchLink>; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Tombozara+N%22">Tombozara N</searchLink>; Institut Malgache de Recherches Appliquées (IMRA), Fondation Albert Et Suzanne Rakoto-Ratsimamanga, Avarabohitra Itaosy, PO Box 3833, Antananarivo, Madagascar. nzara89@gmail.com.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2026 Jun 28. <i>Date of Electronic Publication: </i>2026 Jun 28.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0326264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1912 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200281298%22">00281298 </searchLink><i>NLM ISO Abbreviation: </i>Naunyn Schmiedebergs Arch Pharmacol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42365117
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00210-026-05578-1
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Structure-based immunopharmacological design of a multi-epitope vaccine candidate against Naegleria fowleri targeting TLR3: a pan-genomic and molecular dynamics approach.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Faizan R
      – PersonEntity:
          Name:
            NameFull: Naveed M
      – PersonEntity:
          Name:
            NameFull: Estevez IB
      – PersonEntity:
          Name:
            NameFull: Rehman HM
      – PersonEntity:
          Name:
            NameFull: Latif A
      – PersonEntity:
          Name:
            NameFull: Hammad HM
      – PersonEntity:
          Name:
            NameFull: Khan AR
      – PersonEntity:
          Name:
            NameFull: Alsulami SO
      – PersonEntity:
          Name:
            NameFull: Aljumaa MA
      – PersonEntity:
          Name:
            NameFull: Tombozara N
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 28
              M: 06
              Text: 2026 Jun 28
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1432-1912
          Titles:
            – TitleFull: Naunyn-Schmiedeberg's archives of pharmacology
              Type: main
ResultId 1