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Extracellular vesicles in the tumor microenvironment: Diverse origins, multifaceted functions, and emerging therapeutic opportunities.

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Title: Extracellular vesicles in the tumor microenvironment: Diverse origins, multifaceted functions, and emerging therapeutic opportunities.
Authors: Li Z; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China., Zhang J; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China., Guan H; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China., Yang W; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Chan WH; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China., Li N; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China., Zhong C; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China; Institute for Research and Continuing Education, Hong Kong Baptist University, Shenzhen, China., Zhang G; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China., Yu S; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China., Lyu A; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China. Electronic address: aipinglu@hkbu.edu.hk., Liu J; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China. Electronic address: liujin@hkbu.edu.hk.
Source: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2026 Jun 28; Vol. 295, pp. 189-208. Date of Electronic Publication: 2026 Jun 28.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101280339 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1810 (Electronic) Linking ISSN: 18781810 NLM ISO Abbreviation: Transl Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Extracellular vesicles in the tumor microenvironment: Diverse origins, multifaceted functions, and emerging therapeutic opportunities.
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  Data: <searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Guan+H%22">Guan H</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yang+W%22">Yang W</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+WH%22">Chan WH</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Zhong+C%22">Zhong C</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China; Institute for Research and Continuing Education, Hong Kong Baptist University, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yu+S%22">Yu S</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lyu+A%22">Lyu A</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China. Electronic address: aipinglu@hkbu.edu.hk.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China; Institute of Systems Medicine and Health Sciences, Hong Kong Baptist University, Hong Kong SAR, China; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China. Electronic address: liujin@hkbu.edu.hk.
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      – Type: doi
        Value: 10.1016/j.trsl.2026.06.021
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      – Code: eng
        Text: English
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        StartPage: 189
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      – TitleFull: Extracellular vesicles in the tumor microenvironment: Diverse origins, multifaceted functions, and emerging therapeutic opportunities.
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            – D: 28
              M: 06
              Text: 2026 Jun 28
              Type: published
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