A controlled human infection model for symptomatic pertussis in North America using the pertactin-producing clinical isolate D420.
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| Title: | A controlled human infection model for symptomatic pertussis in North America using the pertactin-producing clinical isolate D420. |
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| Authors: | ElSherif MS; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada.; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada., Redden KL; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada., Langley JM; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada.; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Community Health and Epidemiology, Dalhousie University, Nova Scotia, Canada., Ye L; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada., Blanchard W; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada., Smith B; Department of Mathematics and Statistics, Dalhousie University, Halifax, Nova Scotia, Canada., Wang J; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada.; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada., Abu-Raya B; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada.; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada., Filliter JH; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada., Edwards KM; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Creech CB; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., McNeil S; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada.; Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada., Hatchette TF; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada.; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.; Division of Microbiology, Department of Pathology and Laboratory Medicine, Nova Scotia Health, Halifax, Nova Scotia, Canada., LeBlanc JJ; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada.; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.; Division of Microbiology, Department of Pathology and Laboratory Medicine, Nova Scotia Health, Halifax, Nova Scotia, Canada., Hariri S; Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Pawloski L; Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Maniatis P; Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Fox LM; Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Whittle CA; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada., Halperin SA; Canadian Center for Vaccinology (Dalhousie University, IWK Health, Nova Scotia Health), Halifax, NS, Canada.; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada. |
| Source: | MedRxiv : the preprint server for health sciences [medRxiv] 2026 Jun 15. Date of Electronic Publication: 2026 Jun 15. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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