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DMXAA accelerates orthodontic tooth movement via macrophage-mediated Rab13-enriched extracellular vesicle release and chemokine secretion.

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Title: DMXAA accelerates orthodontic tooth movement via macrophage-mediated Rab13-enriched extracellular vesicle release and chemokine secretion.
Authors: Wang Y; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.; Department of Stomatology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China., Zhang K; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China., Sun X; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China., Xu H; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China., Gu H; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China., Jin Z; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China., Zhu L; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China., Zhang H; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China. hanwenzhang@njmu.edu.cn., Yan B; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China. byan@njmu.edu.cn.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China. byan@njmu.edu.cn.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China. byan@njmu.edu.cn.
Source: Progress in orthodontics [Prog Orthod] 2026 Jun 29; Vol. 27 (1). Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 100936353 Publication Model: Electronic Cited Medium: Internet ISSN: 2196-1042 (Electronic) Linking ISSN: 17237785 NLM ISO Abbreviation: Prog Orthod Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: DMXAA accelerates orthodontic tooth movement via macrophage-mediated Rab13-enriched extracellular vesicle release and chemokine secretion.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.; Department of Stomatology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+K%22">Zhang K</searchLink>; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Sun+X%22">Sun X</searchLink>; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Gu+H%22">Gu H</searchLink>; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Jin+Z%22">Jin Z</searchLink>; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China. hanwenzhang@njmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yan+B%22">Yan B</searchLink>; Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China. byan@njmu.edu.cn.; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China. byan@njmu.edu.cn.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China. byan@njmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100936353%22">Progress in orthodontics</searchLink> [Prog Orthod] 2026 Jun 29; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Jun 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>100936353 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2196-1042 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217237785%22">17237785 </searchLink><i>NLM ISO Abbreviation: </i>Prog Orthod <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s40510-026-00635-0
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        Text: English
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      – TitleFull: DMXAA accelerates orthodontic tooth movement via macrophage-mediated Rab13-enriched extracellular vesicle release and chemokine secretion.
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              M: 06
              Text: 2026 Jun 29
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              Y: 2026
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