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Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort.

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Title: Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort.
Authors: Cholerton B; Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America., Godrich D; Dr. John T Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Pasteris J; John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Rivero J; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America., Martin ER; Dr. John T Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.; John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Kunkle BW; Dr. John T Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.; John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Naj AC; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Hamilton-Nelson KL; John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Wang H; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Lee WP; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Dumitrescu L; Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Hohman TJ; Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Mayeux R; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York City, New York, United States of America.; Gertrude H. Sergievsky Center, Columbia University, New York City, New York, United States of America.; Department of Neurology, College of Physicians and Surgeons, Columbia University and the New York Presbyterian Hospital, New York City, New York, United States of America.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, New York, United States of America., Larson EB; Kaiser Permanente Washington Health Research Institute, Seattle, Washington, United States of America., Crane PK; Department of Medicine, Division of General Internal Medicine, University of Washington, Harborview Medical Center, Seattle, Washington, United States of America., Keene CD; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America., Latimer CS; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America., Mukherjee S; Division of General Internal Medicine, Department of Medicine, University of Washington, Seattle, United States of America., Kofler JK; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Kamboh MI; Department of Human Genetics, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America.; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America., Molina-Porcel L; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Fundació Recerca Clínic Barcelona (FRCB), Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.; Neurological Tissue Bank of the Biobanc-Hospital Clínic-IDIBAPS, Barcelona, Spain., Cuccaro M; Dr. John T Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.; John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Pericak-Vance MA; Dr. John T Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.; John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Rundek T; Department of Neurology, Evelyn F. McKnight Brain Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America., Scott WK; Dr. John T Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.; John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America., Kukull W; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America., Schellenberg G; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Beecham GW; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America., Montine TJ; Department of Pathology, Stanford University School of Medicine, Stanford, California, United States of America.
Corporate Authors: Alzheimer’s Disease Genetics Consortium
Source: PLoS genetics [PLoS Genet] 2026 Jun 29; Vol. 22 (6), pp. e1012170. Date of Electronic Publication: 2026 Jun 29 (Print Publication: 2026).
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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