Antimicrobial peptoids pass rapidly through bacterial membranes and flocculate ribosomes and DNA: A single-cell fluorescence study.

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Title: Antimicrobial peptoids pass rapidly through bacterial membranes and flocculate ribosomes and DNA: A single-cell fluorescence study.
Authors: Zhu Y; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706., Nielsen JE; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305.; Department of Science and Environment, Roskilde University, Roskilde 4000, Denmark., Molchanova N; The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720., Mustafi M; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706., Herlan C; Institute of Biological and Chemical Systems-Functional Molecular Systems, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany., Fleck B; Institute of Biological and Chemical Systems-Functional Molecular Systems, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany., Bräse S; Institute of Biological and Chemical Systems-Functional Molecular Systems, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany., Schepers U; Institute of Functional Interfaces, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany., Sørensen K; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305., Zielke C; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305., Lin JS; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305., Weisshaar JC; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706., Jenssen H; Department of Science and Environment, Roskilde University, Roskilde 4000, Denmark., Barron AE; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jul 07; Vol. 123 (27), pp. e2535920123. Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706.<br /><searchLink fieldCode="AU" term="%22Nielsen+JE%22">Nielsen JE</searchLink>; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305.; Department of Science and Environment, Roskilde University, Roskilde 4000, Denmark.<br /><searchLink fieldCode="AU" term="%22Molchanova+N%22">Molchanova N</searchLink>; The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.<br /><searchLink fieldCode="AU" term="%22Mustafi+M%22">Mustafi M</searchLink>; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706.<br /><searchLink fieldCode="AU" term="%22Herlan+C%22">Herlan C</searchLink>; Institute of Biological and Chemical Systems-Functional Molecular Systems, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany.<br /><searchLink fieldCode="AU" term="%22Fleck+B%22">Fleck B</searchLink>; Institute of Biological and Chemical Systems-Functional Molecular Systems, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany.<br /><searchLink fieldCode="AU" term="%22Bräse+S%22">Bräse S</searchLink>; Institute of Biological and Chemical Systems-Functional Molecular Systems, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany.<br /><searchLink fieldCode="AU" term="%22Schepers+U%22">Schepers U</searchLink>; Institute of Functional Interfaces, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany.<br /><searchLink fieldCode="AU" term="%22Sørensen+K%22">Sørensen K</searchLink>; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Zielke+C%22">Zielke C</searchLink>; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Lin+JS%22">Lin JS</searchLink>; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Weisshaar+JC%22">Weisshaar JC</searchLink>; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706.<br /><searchLink fieldCode="AU" term="%22Jenssen+H%22">Jenssen H</searchLink>; Department of Science and Environment, Roskilde University, Roskilde 4000, Denmark.<br /><searchLink fieldCode="AU" term="%22Barron+AE%22">Barron AE</searchLink>; Department of Bioengineering, Schools of Medicine and of Engineering, Stanford University, Stanford, CA 94305.
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