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Regulatory mechanisms driven by functional 3'-UTR variants in alcohol use disorder and related traits.

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Title: Regulatory mechanisms driven by functional 3'-UTR variants in alcohol use disorder and related traits.
Authors: Chen AB; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA., Yu X; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Rupp JM; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Chu X; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Thapa KS; Department of Biochemistry, Molecular Biology, and Pharmacology, Indiana University School of Medicine, Indianapolis, IN, USA., Gao H; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN, USA., Reiter JL; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA., Xuei X; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN, USA., Tsai AP; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Landreth GE; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, USA., Wang Y; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Foroud TM; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Tischfield JA; Department of Genetics, Rutgers University, Piscataway, NJ, USA., Lai D; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA., Zhang P; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Biostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA., Edenberg HJ; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA. edenberg@iu.edu.; Department of Biochemistry, Molecular Biology, and Pharmacology, Indiana University School of Medicine, Indianapolis, IN, USA. edenberg@iu.edu., Liu Y; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA. yunliu@iu.edu.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA. yunliu@iu.edu.; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN, USA. yunliu@iu.edu.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA. yunliu@iu.edu.
Source: Genome biology [Genome Biol] 2026 Jun 29. Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Regulatory mechanisms driven by functional 3'-UTR variants in alcohol use disorder and related traits.
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  Data: <searchLink fieldCode="AU" term="%22Chen+AB%22">Chen AB</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Rupp+JM%22">Rupp JM</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Chu+X%22">Chu X</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Thapa+KS%22">Thapa KS</searchLink>; Department of Biochemistry, Molecular Biology, and Pharmacology, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Gao+H%22">Gao H</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Reiter+JL%22">Reiter JL</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Xuei+X%22">Xuei X</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Tsai+AP%22">Tsai AP</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Landreth+GE%22">Landreth GE</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Foroud+TM%22">Foroud TM</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Tischfield+JA%22">Tischfield JA</searchLink>; Department of Genetics, Rutgers University, Piscataway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Lai+D%22">Lai D</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Biostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Edenberg+HJ%22">Edenberg HJ</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA. edenberg@iu.edu.; Department of Biochemistry, Molecular Biology, and Pharmacology, Indiana University School of Medicine, Indianapolis, IN, USA. edenberg@iu.edu.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA. yunliu@iu.edu.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA. yunliu@iu.edu.; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN, USA. yunliu@iu.edu.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA. yunliu@iu.edu.
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        Value: 10.1186/s13059-026-04176-x
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        Text: English
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