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Pd/C-Catalyzed Hydrogenation of CF3-, CF2H-, and CF2CO2Et-containing Pyridines: A Robust Method for Highly Functionalized containing Piperidines.

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Title: Pd/C-Catalyzed Hydrogenation of CF3-, CF2H-, and CF2CO2Et-containing Pyridines: A Robust Method for Highly Functionalized containing Piperidines.
Authors: Charvillat T; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France., Bernardelli P; Sanofi R&D, 13 Quai Jules Guesde, Vitry Sur Seine, France., Daumas M; Responsable De C&BD Science & innovation, Sanofi-Aventis R&D, 371 Rue Du Prof. J. Blayac, Montpellier, France., Pannecoucke X; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France., Ferey V; Sanofi Winthrop Industrie/MSAT/ Site d'aramon, Route d'Avignon, Aramon, France., Oulyadi H; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France., Sebban M; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France., Besset T; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France.
Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2026 Jun 30, pp. e4352204. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pd/C-Catalyzed Hydrogenation of CF<subscript>3</subscript>-, CF<subscript>2</subscript>H-, and CF<subscript>2</subscript>CO<subscript>2</subscript>Et-containing Pyridines: A Robust Method for Highly Functionalized containing Piperidines.
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  Data: <searchLink fieldCode="AU" term="%22Charvillat+T%22">Charvillat T</searchLink>; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France.<br /><searchLink fieldCode="AU" term="%22Bernardelli+P%22">Bernardelli P</searchLink>; Sanofi R&D, 13 Quai Jules Guesde, Vitry Sur Seine, France.<br /><searchLink fieldCode="AU" term="%22Daumas+M%22">Daumas M</searchLink>; Responsable De C&BD Science & innovation, Sanofi-Aventis R&D, 371 Rue Du Prof. J. Blayac, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Pannecoucke+X%22">Pannecoucke X</searchLink>; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France.<br /><searchLink fieldCode="AU" term="%22Ferey+V%22">Ferey V</searchLink>; Sanofi Winthrop Industrie/MSAT/ Site d'aramon, Route d'Avignon, Aramon, France.<br /><searchLink fieldCode="AU" term="%22Oulyadi+H%22">Oulyadi H</searchLink>; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France.<br /><searchLink fieldCode="AU" term="%22Sebban+M%22">Sebban M</searchLink>; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France.<br /><searchLink fieldCode="AU" term="%22Besset+T%22">Besset T</searchLink>; INSA Rouen Normandie, Univ Rouen Normandie, Univ Caen Normandie, ENSICAEN, CNRS, Institut CARMeN (UMR 6064), Rouen, France.
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  Data: <searchLink fieldCode="JN" term="%220370543%22">Angewandte Chemie (International ed. in English)</searchLink> [Angew Chem Int Ed Engl] 2026 Jun 30, pp. e4352204. <i>Date of Electronic Publication: </i>2026 Jun 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-VCH%22">Wiley-VCH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0370543 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-3773 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214337851%22">14337851 </searchLink><i>NLM ISO Abbreviation: </i>Angew Chem Int Ed Engl <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 30
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