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Development and validation of diagnostic prediction models for central precocious puberty in girls based on machine learning: a multicenter retrospective study.

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Title: Development and validation of diagnostic prediction models for central precocious puberty in girls based on machine learning: a multicenter retrospective study.
Authors: Wu W; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China., Su Z; Department of Endocrinology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China., Wei H; Department of Endocrinology, Genetics and Metabolism, Henan Children's Hospital (Children's Hospital Affiliated to Zhengzhou University), Zhengzhou, Henan, China., Li Y; Department of Pediatrics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Zhu B; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China., Yuan X; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China., Lei D; Department of Endocrinology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China., Wei Y; Department of Endocrinology, Genetics and Metabolism, Henan Children's Hospital (Children's Hospital Affiliated to Zhengzhou University), Zhengzhou, Henan, China., Wu X; Department of Pediatrics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China., Ou H; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China., Chen X; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China., Zhu Z; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China., Chen R; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 Jun 15; Vol. 17, pp. 1857867. Date of Electronic Publication: 2026 Jun 15 (Print Publication: 2026).
Publication Type: Journal Article; Multicenter Study; Validation Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development and validation of diagnostic prediction models for central precocious puberty in girls based on machine learning: a multicenter retrospective study.
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  Data: <searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Su+Z%22">Su Z</searchLink>; Department of Endocrinology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Wei+H%22">Wei H</searchLink>; Department of Endocrinology, Genetics and Metabolism, Henan Children's Hospital (Children's Hospital Affiliated to Zhengzhou University), Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Pediatrics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhu+B%22">Zhu B</searchLink>; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Yuan+X%22">Yuan X</searchLink>; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Lei+D%22">Lei D</searchLink>; Department of Endocrinology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Wei+Y%22">Wei Y</searchLink>; Department of Endocrinology, Genetics and Metabolism, Henan Children's Hospital (Children's Hospital Affiliated to Zhengzhou University), Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Department of Pediatrics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Ou+H%22">Ou H</searchLink>; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Department of Endocrinology, Genetics and Metabolism, Fuzhou First General Hospital Affiliated with Fujian Medical University (Fuzhou Children's Hospital of Fujian Province), Fuzhou, Fujian, China.
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  Data: <searchLink fieldCode="JN" term="%22101555782%22">Frontiers in endocrinology</searchLink> [Front Endocrinol (Lausanne)] 2026 Jun 15; Vol. 17, pp. 1857867. <i>Date of Electronic Publication: </i>2026 Jun 15 (<i>Print Publication: </i>2026).
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  Data: Journal Article; Multicenter Study; Validation Study; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101555782 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-2392 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216642392%22">16642392 </searchLink><i>NLM ISO Abbreviation: </i>Front Endocrinol (Lausanne) <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fendo.2026.1857867
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        Text: English
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              Text: 2026 Jun 15
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