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Case Report: Successful treatment of pyoderma gangrenosum-like granulomatous liver disease without skin lesions using a TNF-alpha inhibitor.

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Title: Case Report: Successful treatment of pyoderma gangrenosum-like granulomatous liver disease without skin lesions using a TNF-alpha inhibitor.
Authors: Panne I; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland., Matter M; Department of Pathology, University Hospital, Basel, Switzerland., Vosbeck J; Department of Pathology, University Hospital, Basel, Switzerland., von Rotz M; Department of Infectious Diseases, University Hospital, Basel, Switzerland., Steinemann A; Department of Ophthalmology, University Hospital, Basel, Switzerland., Trendelenburg M; University Hospital Basel and Clinical Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland., Heim MH; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University of Basel, Basel, Switzerland., Schirmacher P; Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany., De Gottardi A; Gastroenterology and Hepatology, Luzerner Kantonsspital, Luzern, Switzerland.; Università della Svizzera Italiana, Faculty of Biomedical Sciences, Lugano, Switzerland., Lohse AW; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Terracciano LM; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Bernsmeier C; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University of Basel, Basel, Switzerland.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 15; Vol. 17, pp. 1811910. Date of Electronic Publication: 2026 Jun 15 (Print Publication: 2026).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Case Report: Successful treatment of pyoderma gangrenosum-like granulomatous liver disease without skin lesions using a TNF-alpha inhibitor.
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  Data: <searchLink fieldCode="AU" term="%22Panne+I%22">Panne I</searchLink>; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Matter+M%22">Matter M</searchLink>; Department of Pathology, University Hospital, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vosbeck+J%22">Vosbeck J</searchLink>; Department of Pathology, University Hospital, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22von+Rotz+M%22">von Rotz M</searchLink>; Department of Infectious Diseases, University Hospital, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Steinemann+A%22">Steinemann A</searchLink>; Department of Ophthalmology, University Hospital, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Trendelenburg+M%22">Trendelenburg M</searchLink>; University Hospital Basel and Clinical Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Heim+MH%22">Heim MH</searchLink>; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schirmacher+P%22">Schirmacher P</searchLink>; Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22De+Gottardi+A%22">De Gottardi A</searchLink>; Gastroenterology and Hepatology, Luzerner Kantonsspital, Luzern, Switzerland.; Università della Svizzera Italiana, Faculty of Biomedical Sciences, Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lohse+AW%22">Lohse AW</searchLink>; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Terracciano+LM%22">Terracciano LM</searchLink>; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bernsmeier+C%22">Bernsmeier C</searchLink>; University Centre for Gastrointestinal and Liver Diseases, University Hospital, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University of Basel, Basel, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 15; Vol. 17, pp. 1811910. <i>Date of Electronic Publication: </i>2026 Jun 15 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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