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The Safety and Effectiveness of Early Anti-Tumor-Necrosis-Factor Therapy for Penetrating Crohn's Disease Complications in Children.

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Title: The Safety and Effectiveness of Early Anti-Tumor-Necrosis-Factor Therapy for Penetrating Crohn's Disease Complications in Children.
Authors: Constant BD; Department of Pediatrics, University of Colorado School of Medicine, Digestive Health Institute, Children's Hospital Colorado, Aurora, Colorado., Feng Y; PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA USA., Huang J; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA, USA., Okraku-Mantey J; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Philadelphia., Adler J; Division of Gastroenterology, Hepatology, and Nutrition, C.S. Mott's Children's Hospital, Ann Arbor, MI, USA., Ali S; Division of Pediatric Gastroenterology, UCSF Benioff Children's Hospital Oakland, Oakland, California., Barry J; Division of Pediatric Gastroenterology, Hepatology & Nutrition, Cleveland Clinic, Cleveland, OH, USA., Cruz R; University of California San Diego, San Diego, CA., Crawford EC; Department of Pediatrics, University of Pittsburgh School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA., Dotson JL; Department of Pediatrics, Section of Gastroenterology, University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock, AR, USA., Ewalt MK; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati School of Medicine, Cincinnati, Ohio., Huang JS; Division of Pediatric Gastroenterology, Rady Children's Hospital and University of California San Diego, San Diego, CA., Kachelries K; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Philadelphia., Kurowski JA; Division of Pediatric Gastroenterology, Hepatology & Nutrition, Cleveland Clinic, Cleveland, OH, USA., Minar P; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati School of Medicine, Cincinnati, Ohio., Mitchel EB; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Philadelphia., Montminy TD; Crohn's and Colitis Center, Division of Gastroenterology and Hepatology, University of Colorado Anschutz, Aurora, Colorado., Morrow R; Department of Pediatrics, University of Colorado School of Medicine, Digestive Health Institute, Children's Hospital Colorado, Aurora, Colorado., Pasternak B; Department of Pediatric Gastroenterology, Phoenix Children's Hospital, Phoenix, Arizona, USA., Rabizadeh S; Department of Pediatrics, Guerin Children's and F. Widjaja Inflammatory Bowel Disease Institute; Cedars-Sinai Health Sciences University., Sauer CG; Emory University School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Healthcare of Atlanta, Georgia., Shapira T; Department of Pediatrics, Guerin Children's and F. Widjaja Inflammatory Bowel Disease Institute; Cedars-Sinai Health Sciences University., Sunseri WM; Department of Pediatrics, University of Pittsburgh School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA., Tarabishy I; Division of Gastroenterology, Hepatology, and Nutrition, C.S. Mott's Children's Hospital, Ann Arbor, MI, USA., Trombler B; Division of Pediatric Gastroenterology, UCSF Benioff Children's Hospital Oakland, Oakland, California., Anupindi SA; Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine. Philadelphia, PA., Baldassano RN; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Philadelphia., de Zoeten EF; Department of Pediatrics, University of Colorado School of Medicine, Digestive Health Institute, Children's Hospital Colorado, Aurora, Colorado., Scott FI; Crohn's and Colitis Center, Division of Gastroenterology and Hepatology, University of Colorado Anschutz, Aurora, Colorado., Albenberg L; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Philadelphia.
Source: The American journal of gastroenterology [Am J Gastroenterol] 2026 Jul 01. Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 0421030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1572-0241 (Electronic) Linking ISSN: 00029270 NLM ISO Abbreviation: Am J Gastroenterol Subsets: MEDLINE
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  Data: The Safety and Effectiveness of Early Anti-Tumor-Necrosis-Factor Therapy for Penetrating Crohn's Disease Complications in Children.
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  Data: <searchLink fieldCode="AU" term="%22Constant+BD%22">Constant BD</searchLink>; Department of Pediatrics, University of Colorado School of Medicine, Digestive Health Institute, Children's Hospital Colorado, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Feng+Y%22">Feng Y</searchLink>; PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Huang+J%22">Huang J</searchLink>; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Okraku-Mantey+J%22">Okraku-Mantey J</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Adler+J%22">Adler J</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, C.S. 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Widjaja Inflammatory Bowel Disease Institute; Cedars-Sinai Health Sciences University.<br /><searchLink fieldCode="AU" term="%22Sauer+CG%22">Sauer CG</searchLink>; Emory University School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Healthcare of Atlanta, Georgia.<br /><searchLink fieldCode="AU" term="%22Shapira+T%22">Shapira T</searchLink>; Department of Pediatrics, Guerin Children's and F. Widjaja Inflammatory Bowel Disease Institute; Cedars-Sinai Health Sciences University.<br /><searchLink fieldCode="AU" term="%22Sunseri+WM%22">Sunseri WM</searchLink>; Department of Pediatrics, University of Pittsburgh School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA.<br /><searchLink fieldCode="AU" term="%22Tarabishy+I%22">Tarabishy I</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, C.S. Mott's Children's Hospital, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Trombler+B%22">Trombler B</searchLink>; Division of Pediatric Gastroenterology, UCSF Benioff Children's Hospital Oakland, Oakland, California.<br /><searchLink fieldCode="AU" term="%22Anupindi+SA%22">Anupindi SA</searchLink>; Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine. Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Baldassano+RN%22">Baldassano RN</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Philadelphia.<br /><searchLink fieldCode="AU" term="%22de+Zoeten+EF%22">de Zoeten EF</searchLink>; Department of Pediatrics, University of Colorado School of Medicine, Digestive Health Institute, Children's Hospital Colorado, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Scott+FI%22">Scott FI</searchLink>; Crohn's and Colitis Center, Division of Gastroenterology and Hepatology, University of Colorado Anschutz, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Albenberg+L%22">Albenberg L</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Philadelphia.
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  Data: <searchLink fieldCode="JN" term="%220421030%22">The American journal of gastroenterology</searchLink> [Am J Gastroenterol] 2026 Jul 01. <i>Date of Electronic Publication: </i>2026 Jul 01.
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