A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.

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Title: A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.
Authors: Mukherjee S; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America., Grouza V; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute, Montreal, Quebec, Canada., Tchung A; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Even A; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America., Yaqubi M; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute, Montreal, Quebec, Canada., Tuznik M; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute, Montreal, Quebec, Canada., Cannon T; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Microbiology and Immunology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada., Recinto SJ; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute, Montreal, Quebec, Canada., Gavino C; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Microbiology and Immunology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada., Bourque MJ; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America., Giguère N; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., McBride H; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute, Montreal, Quebec, Canada., Desjardins M; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Gruenheid S; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Microbiology and Immunology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada., Stratton JA; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute, Montreal, Quebec, Canada., Rudko DA; Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute, Montreal, Quebec, Canada., Trudeau LE; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.; Department of Neurosciences, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.; Courtois Institute for Biomedical Innovation and SNC and CIRCA Research Groups, Université de Montréal, Montreal, Quebec, Canada.
Source: PLoS pathogens [PLoS Pathog] 2026 Jun 30; Vol. 22 (6), pp. e1014315. Date of Electronic Publication: 2026 Jun 30 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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