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Effects of riluzole on excitation-inhibition imbalance and functional connectivity in 22q11.2 deletion syndrome: a multimodal 7-Tesla MRI study.

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Title: Effects of riluzole on excitation-inhibition imbalance and functional connectivity in 22q11.2 deletion syndrome: a multimodal 7-Tesla MRI study.
Authors: Sylvester AL; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands. Electronic address: amy.sylvester@maastrichtuniversity.nl., Spapens JC; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands., Tse DH; Scannexus BV, Maastricht, Netherlands; Max Planck Institute for Empirical Aesthetics, Frankfurt, Germany., Serrarens C; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands; Changes GGZ, Breda, Netherlands., Kappert S; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands., Soons N; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands., Poser BA; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands; Max Planck Institute for Human Development, Berlin, Germany., Linden DE; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands., Ivanov D; Max Planck Institute for Empirical Aesthetics, Frankfurt, Germany; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands., van Amelsvoort T; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands., Vingerhoets C; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands; Advisium 's Heeren Loo Zorggroep, Amersfoort, Netherlands.
Source: Psychiatry research. Neuroimaging [Psychiatry Res Neuroimaging] 2026 Jun 27; Vol. 362, pp. 112279. Date of Electronic Publication: 2026 Jun 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101723001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7506 (Electronic) Linking ISSN: 09254927 NLM ISO Abbreviation: Psychiatry Res Neuroimaging Subsets: MEDLINE
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  Data: Effects of riluzole on excitation-inhibition imbalance and functional connectivity in 22q11.2 deletion syndrome: a multimodal 7-Tesla MRI study.
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  Data: <searchLink fieldCode="AU" term="%22Sylvester+AL%22">Sylvester AL</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands. Electronic address: amy.sylvester@maastrichtuniversity.nl.<br /><searchLink fieldCode="AU" term="%22Spapens+JC%22">Spapens JC</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Tse+DH%22">Tse DH</searchLink>; Scannexus BV, Maastricht, Netherlands; Max Planck Institute for Empirical Aesthetics, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Serrarens+C%22">Serrarens C</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands; Changes GGZ, Breda, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kappert+S%22">Kappert S</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Soons+N%22">Soons N</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Poser+BA%22">Poser BA</searchLink>; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands; Max Planck Institute for Human Development, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Linden+DE%22">Linden DE</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Ivanov+D%22">Ivanov D</searchLink>; Max Planck Institute for Empirical Aesthetics, Frankfurt, Germany; Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Amelsvoort+T%22">van Amelsvoort T</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Vingerhoets+C%22">Vingerhoets C</searchLink>; Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, Netherlands; Advisium 's Heeren Loo Zorggroep, Amersfoort, Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101723001%22">Psychiatry research. Neuroimaging</searchLink> [Psychiatry Res Neuroimaging] 2026 Jun 27; Vol. 362, pp. 112279. <i>Date of Electronic Publication: </i>2026 Jun 27.
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