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Tailoring Antiplatelet Therapy Duration After PFO Closure: Insights From the PROLONG Registry.

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Title: Tailoring Antiplatelet Therapy Duration After PFO Closure: Insights From the PROLONG Registry.
Authors: Gaspardone C; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Rome., Trabattoni D; IRCCS Centro Cardiologico Monzino, Milan, Italy., d'Atri DO; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy., Fraccaro C; Department of Cardiac, Thoracic, Vascular Science and Public Health, University of Padova, Italy., Beneduce A; Cardiac Surgery Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Morosato M; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy., Costa P; Institute of Cardiology, ASST Spedali Civili, University of Brescia, Brescia, Italy., Falasconi G; ⁠Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain., Mazza R; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy., Mager R; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy., Donti A; IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy., Saia F; IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy., Toscano E; Department of Interventional Cardiology, Policlinico di Monza, Monza, Italy., Scalise F; Department of Interventional Cardiology, Policlinico di Monza, Monza, Italy., Patti G; Division of Cardiology, Maggiore della Carità Hospital, Novara, Italy., Nerla R; Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, Cotignola, Italy., Castriota F; Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, Cotignola, Italy., Musto C; Division of Cardiology, San Camillo Hospital, Rome, Italy., Paciaroni M; Department of Neurosciences and Rehabilitation, University of Ferrara, Ferrara, Italy., Burzotta F; Department of Cardiovascular Sciences, IRCCS A. Gemelli University Polyclinic, Rome, Italy., Ricchetti G; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Vella CS; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ferri LA; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Bassanelli G; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ancona MB; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Russo F; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Bellini B; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Barone G; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Slavich M; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Napoli F; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Paci G; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Versaci F; Division of Cardiology, Santa Maria Goretti Hospital, Latina, Italy., Pappone C; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Arrhythmology, IRCCS San Donato, Milan, Italy., Mancone M; Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Rome; Umberto I Hospital, Sapienza University of Rome, Rome, Italy., Tarantini G; Department of Cardiac, Thoracic, Vascular Science and Public Health, University of Padova, Italy., Chieffo A; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy., Metra M; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy., Gaspardone A; Division of Cardiology, S. Eugenio Hospital, Rome, Italy., Montorfano M; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy., Godino C; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address: gaspardone.carlo@hsr.it.
Source: JACC. Advances [JACC Adv] 2026 Jun 30; Vol. 5 (8), pp. 102943. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918419284106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-963X (Electronic) Linking ISSN: 2772963X NLM ISO Abbreviation: JACC Adv
Database: MEDLINE Ultimate
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  Data: Tailoring Antiplatelet Therapy Duration After PFO Closure: Insights From the PROLONG Registry.
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  Data: <searchLink fieldCode="AU" term="%22Gaspardone+C%22">Gaspardone C</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Rome.<br /><searchLink fieldCode="AU" term="%22Trabattoni+D%22">Trabattoni D</searchLink>; IRCCS Centro Cardiologico Monzino, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22d'Atri+DO%22">d'Atri DO</searchLink>; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fraccaro+C%22">Fraccaro C</searchLink>; Department of Cardiac, Thoracic, Vascular Science and Public Health, University of Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Beneduce+A%22">Beneduce A</searchLink>; Cardiac Surgery Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Morosato+M%22">Morosato M</searchLink>; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Costa+P%22">Costa P</searchLink>; Institute of Cardiology, ASST Spedali Civili, University of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Falasconi+G%22">Falasconi G</searchLink>; ⁠Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mazza+R%22">Mazza R</searchLink>; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mager+R%22">Mager R</searchLink>; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Donti+A%22">Donti A</searchLink>; IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Saia+F%22">Saia F</searchLink>; IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Toscano+E%22">Toscano E</searchLink>; Department of Interventional Cardiology, Policlinico di Monza, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Scalise+F%22">Scalise F</searchLink>; Department of Interventional Cardiology, Policlinico di Monza, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Patti+G%22">Patti G</searchLink>; Division of Cardiology, Maggiore della Carità Hospital, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Nerla+R%22">Nerla R</searchLink>; Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, Cotignola, Italy.<br /><searchLink fieldCode="AU" term="%22Castriota+F%22">Castriota F</searchLink>; Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, Cotignola, Italy.<br /><searchLink fieldCode="AU" term="%22Musto+C%22">Musto C</searchLink>; Division of Cardiology, San Camillo Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Paciaroni+M%22">Paciaroni M</searchLink>; Department of Neurosciences and Rehabilitation, University of Ferrara, Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Burzotta+F%22">Burzotta F</searchLink>; Department of Cardiovascular Sciences, IRCCS A. Gemelli University Polyclinic, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ricchetti+G%22">Ricchetti G</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vella+CS%22">Vella CS</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ferri+LA%22">Ferri LA</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bassanelli+G%22">Bassanelli G</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ancona+MB%22">Ancona MB</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Russo+F%22">Russo F</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bellini+B%22">Bellini B</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Barone+G%22">Barone G</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Slavich+M%22">Slavich M</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Napoli+F%22">Napoli F</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Paci+G%22">Paci G</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Versaci+F%22">Versaci F</searchLink>; Division of Cardiology, Santa Maria Goretti Hospital, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Pappone+C%22">Pappone C</searchLink>; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Arrhythmology, IRCCS San Donato, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mancone+M%22">Mancone M</searchLink>; Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Rome; Umberto I Hospital, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Tarantini+G%22">Tarantini G</searchLink>; Department of Cardiac, Thoracic, Vascular Science and Public Health, University of Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Chieffo+A%22">Chieffo A</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Metra+M%22">Metra M</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gaspardone+A%22">Gaspardone A</searchLink>; Division of Cardiology, S. Eugenio Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Montorfano+M%22">Montorfano M</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Godino+C%22">Godino C</searchLink>; Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address: gaspardone.carlo@hsr.it.
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