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Assessment of mitochondrial lipid peroxidation in cells and zebrafish using a targeted mass spectrometry probe.

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Title: Assessment of mitochondrial lipid peroxidation in cells and zebrafish using a targeted mass spectrometry probe.
Authors: Uno S; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK., Caldwell ST; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, Scotland., Prag HA; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK., Yu CS; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK., Lamačová LJ; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK., Torres-López M; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK., James AM; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK., Lopez A; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK; Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge CB2 0XY, UK., Woetzel TA; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK; Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge CB2 0XY, UK., Fleming A; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK; Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge CB2 0XY, UK., Rubinsztein DC; Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge CB2 0XY, UK., Hartley RC; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, Scotland. Electronic address: richard.hartley@glasgow.ac.uk., Murphy MP; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Electronic address: mpm37@cam.ac.uk.
Source: Cell chemical biology [Cell Chem Biol] 2026 Jun 30. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Uno+S%22">Uno S</searchLink>; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Caldwell+ST%22">Caldwell ST</searchLink>; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, Scotland.<br /><searchLink fieldCode="AU" term="%22Prag+HA%22">Prag HA</searchLink>; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Yu+CS%22">Yu CS</searchLink>; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Lamačová+LJ%22">Lamačová LJ</searchLink>; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Torres-López+M%22">Torres-López M</searchLink>; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22James+AM%22">James AM</searchLink>; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Lopez+A%22">Lopez A</searchLink>; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK; Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Woetzel+TA%22">Woetzel TA</searchLink>; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK; Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Fleming+A%22">Fleming A</searchLink>; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK; Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Rubinsztein+DC%22">Rubinsztein DC</searchLink>; Cambridge Institute for Medical Research (CIMR), Department of Genomic Medicine, University of Cambridge, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Hartley+RC%22">Hartley RC</searchLink>; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, Scotland. Electronic address: richard.hartley@glasgow.ac.uk.<br /><searchLink fieldCode="AU" term="%22Murphy+MP%22">Murphy MP</searchLink>; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge CB2 0XY, UK; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Electronic address: mpm37@cam.ac.uk.
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              Text: 2026 Jun 30
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