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Acute anti-obesity treatment with celastrol reduces body weight, cerebral inflammation and metabolic imbalances in mice.

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Title: Acute anti-obesity treatment with celastrol reduces body weight, cerebral inflammation and metabolic imbalances in mice.
Authors: Ferreiro A; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain., Holgado M; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain., González-Alday R; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain., González-Soto S; Department of Cell Biology and Histology, Faculty of Medicine, UCM, Madrid, 28040, Spain., Fernandez-Sevilla LM; Department of Basic Health Sciences, Faculty of Health Sciences, University Rey Juan Carlos, Alcorcón, 28922, Spain., Vicente Á; Department of Cell Biology and Histology, Faculty of Medicine, UCM, Madrid, 28040, Spain.; Stem Cells, Immunity and Cancer Group, Health Research Institute Hospital, 12 de Octubre (I+12), Madrid, Spain., López-Larrubia P; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain. plopez@iib.uam.es.; Biomedical Research Networking Centre On Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain. plopez@iib.uam.es., Lizarbe B; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain. blizarbe@iib.uam.es.; Department of Biochemistry, Autonomous University of Madrid, Madrid, Spain. blizarbe@iib.uam.es.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2026 Jul 01; Vol. 32 (1). Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Acute anti-obesity treatment with celastrol reduces body weight, cerebral inflammation and metabolic imbalances in mice.
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  Data: <searchLink fieldCode="AU" term="%22Ferreiro+A%22">Ferreiro A</searchLink>; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain.<br /><searchLink fieldCode="AU" term="%22Holgado+M%22">Holgado M</searchLink>; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain.<br /><searchLink fieldCode="AU" term="%22González-Alday+R%22">González-Alday R</searchLink>; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain.<br /><searchLink fieldCode="AU" term="%22González-Soto+S%22">González-Soto S</searchLink>; Department of Cell Biology and Histology, Faculty of Medicine, UCM, Madrid, 28040, Spain.<br /><searchLink fieldCode="AU" term="%22Fernandez-Sevilla+LM%22">Fernandez-Sevilla LM</searchLink>; Department of Basic Health Sciences, Faculty of Health Sciences, University Rey Juan Carlos, Alcorcón, 28922, Spain.<br /><searchLink fieldCode="AU" term="%22Vicente+Á%22">Vicente Á</searchLink>; Department of Cell Biology and Histology, Faculty of Medicine, UCM, Madrid, 28040, Spain.; Stem Cells, Immunity and Cancer Group, Health Research Institute Hospital, 12 de Octubre (I+12), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22López-Larrubia+P%22">López-Larrubia P</searchLink>; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain. plopez@iib.uam.es.; Biomedical Research Networking Centre On Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain. plopez@iib.uam.es.<br /><searchLink fieldCode="AU" term="%22Lizarbe+B%22">Lizarbe B</searchLink>; Institute for Biomedical Research Sols-Morreale (IIBM), Spanish National Research Council-Autonomous University of Madrid, c/Arturo Duperier 4, Madrid, 28029, Spain. blizarbe@iib.uam.es.; Department of Biochemistry, Autonomous University of Madrid, Madrid, Spain. blizarbe@iib.uam.es.
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  Data: <searchLink fieldCode="JN" term="%229501023%22">Molecular medicine (Cambridge, Mass.)</searchLink> [Mol Med] 2026 Jul 01; Vol. 32 (1). <i>Date of Electronic Publication: </i>2026 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9501023 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-3658 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210761551%22">10761551 </searchLink><i>NLM ISO Abbreviation: </i>Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s10020-026-01530-4
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              Text: 2026 Jul 01
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              Y: 2026
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