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CTSS regulates macrophage lipid metabolic reprogramming and white matter repair after intracerebral hemorrhage.

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Title: CTSS regulates macrophage lipid metabolic reprogramming and white matter repair after intracerebral hemorrhage.
Authors: Yu X; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Huang H; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Mao D; Zhejiang University School of Medicine, Hangzhou, China., Wu J; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Pan J; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Kuang Y; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Wu Y; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Chen H; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Fan L; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Zheng Y; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Zhou J; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Jiang S; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Wu X; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Zhou H; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Yan W; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China., Zheng H; Zhejiang University School of Medicine, Hangzhou, China., Chen J; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. cjyaway@zju.edu.cn.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China. cjyaway@zju.edu.cn., Chen G; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. d-chengao@zju.edu.cn.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China. d-chengao@zju.edu.cn., Gu C; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. guchiw@zju.edu.cn.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China. guchiw@zju.edu.cn.
Source: Journal of translational medicine [J Transl Med] 2026 Jun 30; Vol. 24 (1). Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CTSS regulates macrophage lipid metabolic reprogramming and white matter repair after intracerebral hemorrhage.
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  Data: <searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+H%22">Huang H</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Mao+D%22">Mao D</searchLink>; Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Pan+J%22">Pan J</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Kuang+Y%22">Kuang Y</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Fan+L%22">Fan L</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiang+S%22">Jiang S</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yan+W%22">Yan W</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink>; Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. cjyaway@zju.edu.cn.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China. cjyaway@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+G%22">Chen G</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. d-chengao@zju.edu.cn.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China. d-chengao@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Gu+C%22">Gu C</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. guchiw@zju.edu.cn.; Zhejiang Key Laboratory of Research and Transformation for Major Neurosurgical Diseases, Hangzhou, China. guchiw@zju.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Jun 30; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Jun 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12967-026-08523-1
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        Text: English
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              Text: 2026 Jun 30
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