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Milk-derived extracellular vesicles loaded with miR-146a-5p as a novel therapeutic strategy for allergic airway inflammation.

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Title: Milk-derived extracellular vesicles loaded with miR-146a-5p as a novel therapeutic strategy for allergic airway inflammation.
Authors: Li CG; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China., Sun Q; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China., Tian T; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China., Wu ZC; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Extracellular Vesicle Research and Clinical Translational Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China., Xie YC; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China., Liu XQ; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China., Zhou ZR; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China., Huang LX; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China., Deng XH; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Extracellular Vesicle Research and Clinical Translational Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China., Yu SL; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China., Fu QL; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Extracellular Vesicle Research and Clinical Translational Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Central Laboratory, The Second Affiliated Hospital of Shandong First Medical University, Tai'an 271000, P.R. China.
Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2026 Jun 10; Vol. 37 (3), pp. 102980. Date of Electronic Publication: 2026 Jun 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Milk-derived extracellular vesicles loaded with miR-146a-5p as a novel therapeutic strategy for allergic airway inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Li+CG%22">Li CG</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Sun+Q%22">Sun Q</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Tian+T%22">Tian T</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Wu+ZC%22">Wu ZC</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Extracellular Vesicle Research and Clinical Translational Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Xie+YC%22">Xie YC</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Liu+XQ%22">Liu XQ</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhou+ZR%22">Zhou ZR</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Huang+LX%22">Huang LX</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Deng+XH%22">Deng XH</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Extracellular Vesicle Research and Clinical Translational Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Yu+SL%22">Yu SL</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.<br /><searchLink fieldCode="AU" term="%22Fu+QL%22">Fu QL</searchLink>; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Department of Allergy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.; Extracellular Vesicle Research and Clinical Translational Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.; Central Laboratory, The Second Affiliated Hospital of Shandong First Medical University, Tai'an 271000, P.R. China.
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              Text: 2026 Jun 10
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