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Multifunctional scaffold inspired by hepatocyte exosomes promotes bone regeneration by regulating osteogenic differentiation via PI3K/AKT pathway.

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Title: Multifunctional scaffold inspired by hepatocyte exosomes promotes bone regeneration by regulating osteogenic differentiation via PI3K/AKT pathway.
Authors: Zhang Y; Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., He J; Department of Neurosurgery, The Union Hospital of Tongji College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zeng Y; Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China., Song Y; Medical Genetics Center, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei Province, 430070, China., Wang Z; Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.; Hubei Key Laboratory of Regenerative Medicine and Multi-disciplinary Translational Research (Huazhong University of Science and Technology), Wuhan, Hubei, 430022, China., Wang Q; Department of Rehabilitation Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610065, China.; Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610065, China., You Z; Division of Biliary Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.; Research Center for Biliary Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China., Sun J; Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Source: Materials today. Bio [Mater Today Bio] 2026 Jun 20; Vol. 39, pp. 103360. Date of Electronic Publication: 2026 Jun 20 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101757228 Publication Model: eCollection Cited Medium: Internet ISSN: 2590-0064 (Electronic) Linking ISSN: 25900064 NLM ISO Abbreviation: Mater Today Bio Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Multifunctional scaffold inspired by hepatocyte exosomes promotes bone regeneration by regulating osteogenic differentiation via PI3K/AKT pathway.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22He+J%22">He J</searchLink>; Department of Neurosurgery, The Union Hospital of Tongji College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zeng+Y%22">Zeng Y</searchLink>; Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.<br /><searchLink fieldCode="AU" term="%22Song+Y%22">Song Y</searchLink>; Medical Genetics Center, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei Province, 430070, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.; Hubei Key Laboratory of Regenerative Medicine and Multi-disciplinary Translational Research (Huazhong University of Science and Technology), Wuhan, Hubei, 430022, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Rehabilitation Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610065, China.; Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610065, China.<br /><searchLink fieldCode="AU" term="%22You+Z%22">You Z</searchLink>; Division of Biliary Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.; Research Center for Biliary Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
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  Data: <searchLink fieldCode="JN" term="%22101757228%22">Materials today. Bio</searchLink> [Mater Today Bio] 2026 Jun 20; Vol. 39, pp. 103360. <i>Date of Electronic Publication: </i>2026 Jun 20 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101757228 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2590-0064 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225900064%22">25900064 </searchLink><i>NLM ISO Abbreviation: </i>Mater Today Bio <i>Subsets: </i>PubMed not MEDLINE
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