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Multi-center validation of a machine learning model for early detection of monoclonal immunoglobulin-related disorders using routine laboratory data.

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Title: Multi-center validation of a machine learning model for early detection of monoclonal immunoglobulin-related disorders using routine laboratory data.
Authors: Hu Y; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China., Hao X; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China., Li X; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China., Tang H; Department of Hematology, Xijing Hospital, Fourth Military Medical University, Xi'an, China., Liu R; College of Clinical Medicine, Xi'an Medical University, Xi'an, China., Yang J; Department of Clinical Laboratory Medicine, 3201 Hospital, Hanzhong, China., Zhang W; Department of Hematology, Shaanxi Provincial People's Hospital, Xi'an, China., Wang J; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China., Liu X; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China., Zhou Y; School of Computer Science, Xianyang Normal University, Xianyang, China., Zhang Y; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China., Zhang J; Department of Clinical Laboratory Medicine, 3201 Hospital, Hanzhong, China., Diao Y; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China., Zhou L; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 16; Vol. 17, pp. 1856505. Date of Electronic Publication: 2026 Jun 16 (Print Publication: 2026).
Publication Type: Journal Article; Multicenter Study; Validation Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Hao+X%22">Hao X</searchLink>; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Tang+H%22">Tang H</searchLink>; Department of Hematology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Liu+R%22">Liu R</searchLink>; College of Clinical Medicine, Xi'an Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Department of Clinical Laboratory Medicine, 3201 Hospital, Hanzhong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Hematology, Shaanxi Provincial People's Hospital, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; School of Computer Science, Xianyang Normal University, Xianyang, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Clinical Laboratory Medicine, 3201 Hospital, Hanzhong, China.<br /><searchLink fieldCode="AU" term="%22Diao+Y%22">Diao Y</searchLink>; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Department of Clinical Laboratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 16; Vol. 17, pp. 1856505. <i>Date of Electronic Publication: </i>2026 Jun 16 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 16
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