Moving beyond anatomy: the future of rectal cancer management is biologically-informed, response-adapted, and patient-centered.

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Title: Moving beyond anatomy: the future of rectal cancer management is biologically-informed, response-adapted, and patient-centered.
Authors: Jethwa KR; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA., Smith JJ; Division of Colorectal Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Sanoff H; Department of Medical Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sanford NN; Department of Radiation Oncology, University of Texas Southwestern, Dallas, TX, USA., Intven MPW; Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands., Kim H; Department of Radiation Oncology, City of Hope, Duarte, CA, USA., Hotca-Cho AE; Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA., Goodman KA; Department of Radiation Oncology, Mount Sinai Icahn School of Medicine, New York, NY, USA., Das P; Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Feng M; Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA., Hong TS; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Appelt A; Department of Oncology, Rigshospitalet & Technical University of Denmark, København, DK, Denmark., Gani C; Department of Radiation Oncology, Universitatsklinikum of Tübingen, Tübingen, Germany., Fokas E; Department of Radiation Oncology, Universitatsklinikum of Koln, Koln, Germany., Romesser PB; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hall WA; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Source: Clinical and translational radiation oncology [Clin Transl Radiat Oncol] 2026 Jun 18; Vol. 60, pp. 101214. Date of Electronic Publication: 2026 Jun 18 (Print Publication: 2026).
Publication Type: Letter
Journal Info: Publisher: Elsevier Ireland Ltd. on behalf of European Society for Radiotherapy and Oncology Country of Publication: Ireland NLM ID: 101713416 Publication Model: eCollection Cited Medium: Internet ISSN: 2405-6308 (Electronic) Linking ISSN: 24056308 NLM ISO Abbreviation: Clin Transl Radiat Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Moving beyond anatomy: the future of rectal cancer management is biologically-informed, response-adapted, and patient-centered.
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  Data: <searchLink fieldCode="AU" term="%22Jethwa+KR%22">Jethwa KR</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Smith+JJ%22">Smith JJ</searchLink>; Division of Colorectal Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Sanoff+H%22">Sanoff H</searchLink>; Department of Medical Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Sanford+NN%22">Sanford NN</searchLink>; Department of Radiation Oncology, University of Texas Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Intven+MPW%22">Intven MPW</searchLink>; Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Department of Radiation Oncology, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hotca-Cho+AE%22">Hotca-Cho AE</searchLink>; Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Goodman+KA%22">Goodman KA</searchLink>; Department of Radiation Oncology, Mount Sinai Icahn School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Das+P%22">Das P</searchLink>; Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Feng+M%22">Feng M</searchLink>; Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hong+TS%22">Hong TS</searchLink>; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Appelt+A%22">Appelt A</searchLink>; Department of Oncology, Rigshospitalet & Technical University of Denmark, København, DK, Denmark.<br /><searchLink fieldCode="AU" term="%22Gani+C%22">Gani C</searchLink>; Department of Radiation Oncology, Universitatsklinikum of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Fokas+E%22">Fokas E</searchLink>; Department of Radiation Oncology, Universitatsklinikum of Koln, Koln, Germany.<br /><searchLink fieldCode="AU" term="%22Romesser+PB%22">Romesser PB</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hall+WA%22">Hall WA</searchLink>; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
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  Data: <searchLink fieldCode="JN" term="%22101713416%22">Clinical and translational radiation oncology</searchLink> [Clin Transl Radiat Oncol] 2026 Jun 18; Vol. 60, pp. 101214. <i>Date of Electronic Publication: </i>2026 Jun 18 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ireland+Ltd%2E+on+behalf+of+European+Society+for+Radiotherapy+and+Oncology%22">Elsevier Ireland Ltd. on behalf of European Society for Radiotherapy and Oncology </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>101713416 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2405-6308 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224056308%22">24056308 </searchLink><i>NLM ISO Abbreviation: </i>Clin Transl Radiat Oncol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Jun 18
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