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Pre-Pectoral Breast Reconstruction after Mastectomy: Current Evidence, Knowledge Gaps, and Rationale for the I-PREPARE EUBREAST-11R Trial.

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Title: Pre-Pectoral Breast Reconstruction after Mastectomy: Current Evidence, Knowledge Gaps, and Rationale for the I-PREPARE EUBREAST-11R Trial.
Authors: Di Micco R; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Scardina L; Breast Unit, Department of Women, Children and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Botteri E; Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway., Banys-Paluchowski M; Department of Obstetrics and Gynecology, Campus Lübeck, University Hospital of Schleswig Holstein, Lübeck, Germany., Cardoso MJ; Breast Cancer Research Program, Breast Unit, Champalimaud Foundation, Lisbon, Portugal.; Lisbon University Faculty of Medicine, Lisbon, Portugal., de Boniface J; Department of Surgery, Capio St. Göran's Hospital, Stockholm, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Gasparri ML; Department of Gynecology and Obstetrics, Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano, Lugano, Switzerland.; Faculty of Biomedicine, University of the Italian Switzerland (USI), Lugano, Switzerland., Gulluoglu BM; Department of Surgery, Breast Surgery Unit, Marmara University School of Medicine and SENATURK Turkish Academy of Senology, Istanbul, Turkey., Kaidar-Person O; Breast Cancer Radiation Therapy Unit, Sheba Medical Center, Ramat Gan, Israel.; Gray School of Medical Sciences, Tel Aviv University, Tel Aviv-Yafo, Israel., Nava MB; Fondazione G.Re.T.A. (Group for Reconstructive and Therapeutic Advancements) ETS, Naples, Italy., Poortmans P; Department of Radiation Oncology, Iridium Netwerk, Wilrijk-Antwerp, Belgium.; Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk-Antwerp, Belgium., Potter S; Bristol Medical School (THS), Bristol Population Health Science Institute, Bristol, UK., Rocco N; Fondazione G.Re.T.A. (Group for Reconstructive and Therapeutic Advancements) ETS, Naples, Italy.; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.; Breast Unit, University of Naples Federico II, Naples, Italy., Spanic T; Europa Donna, European Breast Cancer Coalition, Europa Donna Slovenia, Ljubljana, Slovenia., Thill M; Department of Gynecology and Gynecological Oncology, AGAPLESION Markus Krankenhaus, Frankfurt am Main, Germany., Travado L; Breast Unit, Champalimaud Clinical and Research Center, Champalimaud Foundation, Lisbon, Portugal.; Department of Clinical Health Psychology, Piaget Institute, Lisbon, Portugal., Veselinovic K; Department of Gynecology and Obstetrics, University of Ulm, Ulm, Germany., Weber WP; Basel University Hospital, Basel, Switzerland., Zuber V; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Cisternino G; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Baleri S; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Rampa M; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Corona SP; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Calabretto F; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Ceccarino R; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Rottino A; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy., Franceschini G; Breast Unit, Department of Women, Children and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Kühn T; Department of Gynecology and Obstetrics, University of Ulm, Ulm, Germany., Gentilini OD; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.; Faculty of Medicine, Università Vita-Salute San Raffaele, Milan, Italy.
Corporate Authors: I-PREPARE Study Group
Source: Breast care (Basel, Switzerland) [Breast Care (Basel)] 2026 Jun 05. Date of Electronic Publication: 2026 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: Karger Country of Publication: Switzerland NLM ID: 101254060 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1661-3791 (Print) Linking ISSN: 16613791 NLM ISO Abbreviation: Breast Care (Basel)
Database: MEDLINE Ultimate
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  Data: Pre-Pectoral Breast Reconstruction after Mastectomy: Current Evidence, Knowledge Gaps, and Rationale for the I-PREPARE EUBREAST-11R Trial.
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  Data: <searchLink fieldCode="AU" term="%22Di+Micco+R%22">Di Micco R</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Scardina+L%22">Scardina L</searchLink>; Breast Unit, Department of Women, Children and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Botteri+E%22">Botteri E</searchLink>; Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Banys-Paluchowski+M%22">Banys-Paluchowski M</searchLink>; Department of Obstetrics and Gynecology, Campus Lübeck, University Hospital of Schleswig Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Cardoso+MJ%22">Cardoso MJ</searchLink>; Breast Cancer Research Program, Breast Unit, Champalimaud Foundation, Lisbon, Portugal.; Lisbon University Faculty of Medicine, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22de+Boniface+J%22">de Boniface J</searchLink>; Department of Surgery, Capio St. Göran's Hospital, Stockholm, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Gasparri+ML%22">Gasparri ML</searchLink>; Department of Gynecology and Obstetrics, Ente Ospedaliero Cantonale, Ospedale Regionale di Lugano, Lugano, Switzerland.; Faculty of Biomedicine, University of the Italian Switzerland (USI), Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gulluoglu+BM%22">Gulluoglu BM</searchLink>; Department of Surgery, Breast Surgery Unit, Marmara University School of Medicine and SENATURK Turkish Academy of Senology, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Kaidar-Person+O%22">Kaidar-Person O</searchLink>; Breast Cancer Radiation Therapy Unit, Sheba Medical Center, Ramat Gan, Israel.; Gray School of Medical Sciences, Tel Aviv University, Tel Aviv-Yafo, Israel.<br /><searchLink fieldCode="AU" term="%22Nava+MB%22">Nava MB</searchLink>; Fondazione G.Re.T.A. (Group for Reconstructive and Therapeutic Advancements) ETS, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Poortmans+P%22">Poortmans P</searchLink>; Department of Radiation Oncology, Iridium Netwerk, Wilrijk-Antwerp, Belgium.; Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk-Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Potter+S%22">Potter S</searchLink>; Bristol Medical School (THS), Bristol Population Health Science Institute, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Rocco+N%22">Rocco N</searchLink>; Fondazione G.Re.T.A. (Group for Reconstructive and Therapeutic Advancements) ETS, Naples, Italy.; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.; Breast Unit, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Spanic+T%22">Spanic T</searchLink>; Europa Donna, European Breast Cancer Coalition, Europa Donna Slovenia, Ljubljana, Slovenia.<br /><searchLink fieldCode="AU" term="%22Thill+M%22">Thill M</searchLink>; Department of Gynecology and Gynecological Oncology, AGAPLESION Markus Krankenhaus, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Travado+L%22">Travado L</searchLink>; Breast Unit, Champalimaud Clinical and Research Center, Champalimaud Foundation, Lisbon, Portugal.; Department of Clinical Health Psychology, Piaget Institute, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Veselinovic+K%22">Veselinovic K</searchLink>; Department of Gynecology and Obstetrics, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+WP%22">Weber WP</searchLink>; Basel University Hospital, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zuber+V%22">Zuber V</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cisternino+G%22">Cisternino G</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Baleri+S%22">Baleri S</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rampa+M%22">Rampa M</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Corona+SP%22">Corona SP</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Calabretto+F%22">Calabretto F</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ceccarino+R%22">Ceccarino R</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rottino+A%22">Rottino A</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Franceschini+G%22">Franceschini G</searchLink>; Breast Unit, Department of Women, Children and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Kühn+T%22">Kühn T</searchLink>; Department of Gynecology and Obstetrics, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Gentilini+OD%22">Gentilini OD</searchLink>; Breast Surgery Unit, IRCCS Ospedale San Raffaele, Milan, Italy.; Faculty of Medicine, Università Vita-Salute San Raffaele, Milan, Italy.
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