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Rituximab versus Ocrelizumab in Newly Diagnosed Relapsing Multiple Sclerosis.

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Title: Rituximab versus Ocrelizumab in Newly Diagnosed Relapsing Multiple Sclerosis.
Authors: Torkildsen Ø; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway., Brustad HK; Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, Oslo., Høgestøl EA; Institute of Clinical Medicine, University of Oslo, Oslo.; Department of Neurology, Oslo University Hospital, Oslo., Alstadhaug KB; Department of Neurology, Nordland Hospital Trust, Bodø, Norway., Bhan A; Department of Neurology, Stavanger University Hospital, Stavanger, Norway., Flemmen HØ; Department of Neurology, Telemark Hospital Trust, Skien, Norway., Habbestad A; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway., Høglund RAA; Department of Neurology, Akershus University Hospital, Oslo.; Institute of Basic Medical Sciences, University of Oslo, Oslo., LeBlanc M; Oslo Center for Biostatistics and Epidemiology, University of Oslo, Oslo.; Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo., Lopen P; Department of Neurology, Nord-Trøndelag Hospital Trust, Namsos, Norway., Lorentzen ÅR; Institute of Clinical Medicine, University of Oslo, Oslo.; Department of Neurology, Sørlandet Hospital Trust, Kristiansand, Norway., Morsund ÅH; Department of Neurology, Møre og Romsdal Hospital Trust, Molde, Norway., Lossius A; Department of Neurology, Akershus University Hospital, Oslo.; Institute of Basic Medical Sciences, University of Oslo, Oslo., Lundby R; Department of Neurology, Oslo University Hospital, Oslo.; Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo., Nygaard GO; Institute of Clinical Medicine, University of Oslo, Oslo.; Department of Neurology, Oslo University Hospital, Oslo., Rød BE; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway., Simonsen CS; Department of Neurology, Vestre Viken Hospital Trust, Drammen, Norway., Steffensen L; Department of Neurology, University Hospital North Norway Trust, Tromsø.; Department of Clinical Medicine, Faculty of Health Sciences, Arctic University of Norway, Tromsø., Torgauten H; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway., Piehl F; Department of Neurology, Karolinska University Hospital, Stockholm., Wergeland S; Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Norwegian Multiple Sclerosis Registry and Biobank, Haukeland University Hospital, Bergen, Norway., Myhr KM; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Corporate Authors: OVERLORD-MS Investigators
Source: The New England journal of medicine [N Engl J Med] 2026 Jul 02; Vol. 395 (1), pp. 44-53.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Comparative Study; Equivalence Trial
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rituximab versus Ocrelizumab in Newly Diagnosed Relapsing Multiple Sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Torkildsen+Ø%22">Torkildsen Ø</searchLink>; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Brustad+HK%22">Brustad HK</searchLink>; Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, Oslo.<br /><searchLink fieldCode="AU" term="%22Høgestøl+EA%22">Høgestøl EA</searchLink>; Institute of Clinical Medicine, University of Oslo, Oslo.; Department of Neurology, Oslo University Hospital, Oslo.<br /><searchLink fieldCode="AU" term="%22Alstadhaug+KB%22">Alstadhaug KB</searchLink>; Department of Neurology, Nordland Hospital Trust, Bodø, Norway.<br /><searchLink fieldCode="AU" term="%22Bhan+A%22">Bhan A</searchLink>; Department of Neurology, Stavanger University Hospital, Stavanger, Norway.<br /><searchLink fieldCode="AU" term="%22Flemmen+HØ%22">Flemmen HØ</searchLink>; Department of Neurology, Telemark Hospital Trust, Skien, Norway.<br /><searchLink fieldCode="AU" term="%22Habbestad+A%22">Habbestad A</searchLink>; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Høglund+RAA%22">Høglund RAA</searchLink>; Department of Neurology, Akershus University Hospital, Oslo.; Institute of Basic Medical Sciences, University of Oslo, Oslo.<br /><searchLink fieldCode="AU" term="%22LeBlanc+M%22">LeBlanc M</searchLink>; Oslo Center for Biostatistics and Epidemiology, University of Oslo, Oslo.; Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo.<br /><searchLink fieldCode="AU" term="%22Lopen+P%22">Lopen P</searchLink>; Department of Neurology, Nord-Trøndelag Hospital Trust, Namsos, Norway.<br /><searchLink fieldCode="AU" term="%22Lorentzen+ÅR%22">Lorentzen ÅR</searchLink>; Institute of Clinical Medicine, University of Oslo, Oslo.; Department of Neurology, Sørlandet Hospital Trust, Kristiansand, Norway.<br /><searchLink fieldCode="AU" term="%22Morsund+ÅH%22">Morsund ÅH</searchLink>; Department of Neurology, Møre og Romsdal Hospital Trust, Molde, Norway.<br /><searchLink fieldCode="AU" term="%22Lossius+A%22">Lossius A</searchLink>; Department of Neurology, Akershus University Hospital, Oslo.; Institute of Basic Medical Sciences, University of Oslo, Oslo.<br /><searchLink fieldCode="AU" term="%22Lundby+R%22">Lundby R</searchLink>; Department of Neurology, Oslo University Hospital, Oslo.; Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo.<br /><searchLink fieldCode="AU" term="%22Nygaard+GO%22">Nygaard GO</searchLink>; Institute of Clinical Medicine, University of Oslo, Oslo.; Department of Neurology, Oslo University Hospital, Oslo.<br /><searchLink fieldCode="AU" term="%22Rød+BE%22">Rød BE</searchLink>; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Simonsen+CS%22">Simonsen CS</searchLink>; Department of Neurology, Vestre Viken Hospital Trust, Drammen, Norway.<br /><searchLink fieldCode="AU" term="%22Steffensen+L%22">Steffensen L</searchLink>; Department of Neurology, University Hospital North Norway Trust, Tromsø.; Department of Clinical Medicine, Faculty of Health Sciences, Arctic University of Norway, Tromsø.<br /><searchLink fieldCode="AU" term="%22Torgauten+H%22">Torgauten H</searchLink>; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Piehl+F%22">Piehl F</searchLink>; Department of Neurology, Karolinska University Hospital, Stockholm.<br /><searchLink fieldCode="AU" term="%22Wergeland+S%22">Wergeland S</searchLink>; Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Norwegian Multiple Sclerosis Registry and Biobank, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Myhr+KM%22">Myhr KM</searchLink>; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Massachusetts+Medical+Society%22">Massachusetts Medical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0255562 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1533-4406 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200284793%22">00284793 </searchLink><i>NLM ISO Abbreviation: </i>N Engl J Med <i>Subsets: </i>MEDLINE
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        Value: 10.1056/NEJMoa2600993
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        Text: English
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      – TitleFull: Rituximab versus Ocrelizumab in Newly Diagnosed Relapsing Multiple Sclerosis.
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              Text: 2026 Jul 02
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