Plasma Proteomic Signatures of Left Atrial Dysfunction and Cerebral Small Vessel Disease: Elucidating Heart-Brain Connections.

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Title: Plasma Proteomic Signatures of Left Atrial Dysfunction and Cerebral Small Vessel Disease: Elucidating Heart-Brain Connections.
Authors: Tan ESJ; Department of Cardiology, National University Heart Centre, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address: esjtan@nus.edu.sg., Sim MA; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore; Department of Intensive Care Medicine, Ng Teng Fong General Hospital, Singapore, Singapore., Choi H; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cardiovascular Research Institute, National University Health System, Singapore, Singapore., Chan SP; Cardiovascular Research Institute, National University Health System, Singapore, Singapore., Cai VY; Department of Medicine and Therapeutics, Chinese University of Hong Kong, New Territories, Hong Kong., Gong L; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Venketasubramanian N; Raffles Neuroscience Centre, Singapore, Singapore., Tan BY; St. Luke's Hospital, Singapore, Singapore., Hilal S; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Lai MKP; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ling LH; Department of Cardiology, National University Heart Centre, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cardiovascular Research Institute, National University Health System, Singapore, Singapore., Richards AM; Department of Cardiology, National University Heart Centre, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cardiovascular Research Institute, National University Health System, Singapore, Singapore; Christchurch Heart Institute, University of Otago, Christchurch, New Zealand., Chen C; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address: cchen@nus.edu.sg.
Source: JACC. Basic to translational science [JACC Basic Transl Sci] 2026 Jul 01; Vol. 11 (8), pp. 101622. Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier on behalf of the American College of Cardiology Foundation Country of Publication: United States NLM ID: 101677259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2452-302X (Electronic) Linking ISSN: 2452302X NLM ISO Abbreviation: JACC Basic Transl Sci
Database: MEDLINE Ultimate
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  Data: Plasma Proteomic Signatures of Left Atrial Dysfunction and Cerebral Small Vessel Disease: Elucidating Heart-Brain Connections.
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  Data: <searchLink fieldCode="AU" term="%22Tan+ESJ%22">Tan ESJ</searchLink>; Department of Cardiology, National University Heart Centre, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address: esjtan@nus.edu.sg.<br /><searchLink fieldCode="AU" term="%22Sim+MA%22">Sim MA</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore; Department of Intensive Care Medicine, Ng Teng Fong General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Choi+H%22">Choi H</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cardiovascular Research Institute, National University Health System, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chan+SP%22">Chan SP</searchLink>; Cardiovascular Research Institute, National University Health System, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Cai+VY%22">Cai VY</searchLink>; Department of Medicine and Therapeutics, Chinese University of Hong Kong, New Territories, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Gong+L%22">Gong L</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Venketasubramanian+N%22">Venketasubramanian N</searchLink>; Raffles Neuroscience Centre, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+BY%22">Tan BY</searchLink>; St. Luke's Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Hilal+S%22">Hilal S</searchLink>; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lai+MKP%22">Lai MKP</searchLink>; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ling+LH%22">Ling LH</searchLink>; Department of Cardiology, National University Heart Centre, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cardiovascular Research Institute, National University Health System, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Richards+AM%22">Richards AM</searchLink>; Department of Cardiology, National University Heart Centre, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cardiovascular Research Institute, National University Health System, Singapore, Singapore; Christchurch Heart Institute, University of Otago, Christchurch, New Zealand.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address: cchen@nus.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%22101677259%22">JACC. Basic to translational science</searchLink> [JACC Basic Transl Sci] 2026 Jul 01; Vol. 11 (8), pp. 101622. <i>Date of Electronic Publication: </i>2026 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+on+behalf+of+the+American+College+of+Cardiology+Foundation%22">Elsevier on behalf of the American College of Cardiology Foundation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101677259 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2452-302X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222452302X%22">2452302X </searchLink><i>NLM ISO Abbreviation: </i>JACC Basic Transl Sci
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              Text: 2026 Jul 01
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