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GPNMB-directed CAR T cell therapy against MiT/TFE-family fusion-driven solid tumors.

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Title: GPNMB-directed CAR T cell therapy against MiT/TFE-family fusion-driven solid tumors.
Authors: Zemp FJ; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Breckenridge Z; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Song H; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Gill GS; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Louie TL; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Narta K; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Liu H; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Suh Y; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Guignard L; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Mandujano-Tinoco EA; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada., Collao N; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada., Pyczek J; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Ellestad KK; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Curry J; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Robson DNA Science Centre, University of Calgary, Calgary, Alberta, Canada., Langley J; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Robson DNA Science Centre, University of Calgary, Calgary, Alberta, Canada., John C; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Mah LK; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Rajwani J; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Evseev D; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Turk M; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Benaoudia S; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Alex J; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Naumenko V; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Manoharan VT; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Mehrabadi MK; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Smith HA; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Gilbert GNY; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Gillmor A; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Verhey TB; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Todesco HM; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada., Osz K; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Ahn BY; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Bogossian A; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Anderson C; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Sikdar S; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Rukunuddin S; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Bismar TA; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Heng DYC; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Lawson K; Division of Urology, Department of Surgery, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Ontario, Canada.; Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, USA., Linehan WM; Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, USA., Pedersen H; Centre for Health Genomics and Informatics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Gordon PMK; Centre for Health Genomics and Informatics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., McIntyre JB; Cancer Translational Research Core Laboratory, Arthur JE Child Comprehensive Cancer Centre, Calgary, Alberta, Canada., MacGregor J; Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Garzia L; Department of Surgery, McGill University, Montreal, Québec, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, Québec, Canada., Brodeur-Robb K; C17 Council, Edmonton, Alberta, Canada., DiFrancesco L; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Ogilvie T; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Schöffski P; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven, Belgium.; Department of Oncology, Research Unit Laboratory of Experimental Oncology, KU Leuven, Belgium., Wozniak A; Department of Oncology, Research Unit Laboratory of Experimental Oncology, KU Leuven, Belgium., Holt RA; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; Canada's Michael Smith Genome Sciences Centre, Vancouver, British Columbia, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada., Bell J; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Senger DL; Gerald Bronfman Department of Oncology, McGill University, Montreal, Québec, Canada.; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada., Lewis V; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Monument M; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Department of Surgery and Orthopedic Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Khan O; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Baudrier L; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Robson DNA Science Centre, University of Calgary, Calgary, Alberta, Canada., Billon P; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Robson DNA Science Centre, University of Calgary, Calgary, Alberta, Canada., Gabriel V; Dept of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Biernaskie J; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.; Department of Surgery and Orthopedic Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Potts K; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada., Trpkov K; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Diagnostic and Molecular Pathology, Alberta Precision Laboratories, Calgary, Alberta, Canada., Hay K; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Medicine, Division of Hematology and Hematologic Malignancies, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Quizi J; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Center for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Chan J; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Saleh R; Gerald Bronfman Department of Oncology, McGill University, Montreal, Québec, Canada.; Division of Medical Oncology, McGill University Health Centre, Montreal, Québec, Canada., Henning JW; Arthur Child Comprehensive Cancer Centre, Calgary, Alberta, Canada., Prokopishyn NL; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Shafey M; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Medicine, Division of Hematology and Hematologic Malignancies, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Morrissy AS; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Mahoney DJ; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada. djmahone@ucalgary.ca.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada. djmahone@ucalgary.ca.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. djmahone@ucalgary.ca.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. djmahone@ucalgary.ca.
Source: Nature cancer [Nat Cancer] 2026 Jul 01. Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: GPNMB-directed CAR T cell therapy against MiT/TFE-family fusion-driven solid tumors.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Zemp+FJ%22">Zemp FJ</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Breckenridge+Z%22">Breckenridge Z</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Song+H%22">Song H</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Gill+GS%22">Gill GS</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Louie+TL%22">Louie TL</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Narta+K%22">Narta K</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Suh+Y%22">Suh Y</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Guignard+L%22">Guignard L</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Mandujano-Tinoco+EA%22">Mandujano-Tinoco EA</searchLink>; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Collao+N%22">Collao N</searchLink>; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Pyczek+J%22">Pyczek J</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Ellestad+KK%22">Ellestad KK</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Curry+J%22">Curry J</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Robson DNA Science Centre, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Langley+J%22">Langley J</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Robson DNA Science Centre, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22John+C%22">John C</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Mah+LK%22">Mah LK</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Rajwani+J%22">Rajwani J</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Evseev+D%22">Evseev D</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Turk+M%22">Turk M</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Benaoudia+S%22">Benaoudia S</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Alex+J%22">Alex J</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Naumenko+V%22">Naumenko V</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Manoharan+VT%22">Manoharan VT</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Mehrabadi+MK%22">Mehrabadi MK</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Smith+HA%22">Smith HA</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Gilbert+GNY%22">Gilbert GNY</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Gillmor+A%22">Gillmor A</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Verhey+TB%22">Verhey TB</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Todesco+HM%22">Todesco HM</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Osz+K%22">Osz K</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Ahn+BY%22">Ahn BY</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Bogossian+A%22">Bogossian A</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Anderson+C%22">Anderson C</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Sikdar+S%22">Sikdar S</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Rukunuddin+S%22">Rukunuddin S</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Bismar+TA%22">Bismar TA</searchLink>; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Heng+DYC%22">Heng DYC</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Lawson+K%22">Lawson K</searchLink>; Division of Urology, Department of Surgery, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Ontario, Canada.; Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Linehan+WM%22">Linehan WM</searchLink>; Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pedersen+H%22">Pedersen H</searchLink>; Centre for Health Genomics and Informatics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Gordon+PMK%22">Gordon PMK</searchLink>; Centre for Health Genomics and Informatics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22McIntyre+JB%22">McIntyre JB</searchLink>; Cancer Translational Research Core Laboratory, Arthur JE Child Comprehensive Cancer Centre, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22MacGregor+J%22">MacGregor J</searchLink>; Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Garzia+L%22">Garzia L</searchLink>; Department of Surgery, McGill University, Montreal, Québec, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Brodeur-Robb+K%22">Brodeur-Robb K</searchLink>; C17 Council, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22DiFrancesco+L%22">DiFrancesco L</searchLink>; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Ogilvie+T%22">Ogilvie T</searchLink>; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Schöffski+P%22">Schöffski P</searchLink>; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven, Belgium.; Department of Oncology, Research Unit Laboratory of Experimental Oncology, KU Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Wozniak+A%22">Wozniak A</searchLink>; Department of Oncology, Research Unit Laboratory of Experimental Oncology, KU Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Holt+RA%22">Holt RA</searchLink>; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; Canada's Michael Smith Genome Sciences Centre, Vancouver, British Columbia, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Bell+J%22">Bell J</searchLink>; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Senger+DL%22">Senger DL</searchLink>; Gerald Bronfman Department of Oncology, McGill University, Montreal, Québec, Canada.; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Lewis+V%22">Lewis V</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Monument+M%22">Monument M</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Department of Surgery and Orthopedic Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Khan+O%22">Khan O</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Baudrier+L%22">Baudrier L</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Robson DNA Science Centre, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Billon+P%22">Billon P</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Robson DNA Science Centre, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Gabriel+V%22">Gabriel V</searchLink>; Dept of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Biernaskie+J%22">Biernaskie J</searchLink>; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.; Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.; Department of Surgery and Orthopedic Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Potts+K%22">Potts K</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Trpkov+K%22">Trpkov K</searchLink>; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Diagnostic and Molecular Pathology, Alberta Precision Laboratories, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Hay+K%22">Hay K</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Medicine, Division of Hematology and Hematologic Malignancies, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Quizi+J%22">Quizi J</searchLink>; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Center for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Chan+J%22">Chan J</searchLink>; Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Saleh+R%22">Saleh R</searchLink>; Gerald Bronfman Department of Oncology, McGill University, Montreal, Québec, Canada.; Division of Medical Oncology, McGill University Health Centre, Montreal, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Henning+JW%22">Henning JW</searchLink>; Arthur Child Comprehensive Cancer Centre, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Prokopishyn+NL%22">Prokopishyn NL</searchLink>; 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Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada. djmahone@ucalgary.ca.; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada. djmahone@ucalgary.ca.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. djmahone@ucalgary.ca.; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. djmahone@ucalgary.ca.
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  Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2026 Jul 01. <i>Date of Electronic Publication: </i>2026 Jul 01.
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