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Cross-ancestry pleiotropic analysis of imaging-derived phenotypes enhances risk stratification of depression.

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Title: Cross-ancestry pleiotropic analysis of imaging-derived phenotypes enhances risk stratification of depression.
Authors: Feng Y; Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Guo X; Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Huang P; Department of Epidemiology, Centre for Global Health, School of Public Health, National Vaccine Innovation Platform, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, Jiangsu, 211166, China., Jia N; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China., Hu S; Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. dorhushaohua@zju.edu.cn.; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China. dorhushaohua@zju.edu.cn.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China. dorhushaohua@zju.edu.cn.; The Zhejiang Key Laboratory of Precision Psychiatry, Hangzhou, 310003, China. dorhushaohua@zju.edu.cn.; The State Key Lab of Brain-Machine Intelligence, Zhejiang University, Hangzhou, China. dorhushaohua@zju.edu.cn.; MOE Frontier Science Center for Brain Science and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou, 310003, China. dorhushaohua@zju.edu.cn.; Brain Research Institute of Zhejiang University, Hangzhou, 310003, China. dorhushaohua@zju.edu.cn.; Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou, 310003, China. dorhushaohua@zju.edu.cn., Yang S; Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, 15224, USA. shy229@pitt.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jul 01. Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cross-ancestry pleiotropic analysis of imaging-derived phenotypes enhances risk stratification of depression.
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  Data: <searchLink fieldCode="AU" term="%22Feng+Y%22">Feng Y</searchLink>; Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Guo+X%22">Guo X</searchLink>; Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Huang+P%22">Huang P</searchLink>; Department of Epidemiology, Centre for Global Health, School of Public Health, National Vaccine Innovation Platform, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, Jiangsu, 211166, China.<br /><searchLink fieldCode="AU" term="%22Jia+N%22">Jia N</searchLink>; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Hu+S%22">Hu S</searchLink>; Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. dorhushaohua@zju.edu.cn.; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China. dorhushaohua@zju.edu.cn.; Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China. dorhushaohua@zju.edu.cn.; The Zhejiang Key Laboratory of Precision Psychiatry, Hangzhou, 310003, China. dorhushaohua@zju.edu.cn.; The State Key Lab of Brain-Machine Intelligence, Zhejiang University, Hangzhou, China. dorhushaohua@zju.edu.cn.; MOE Frontier Science Center for Brain Science and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou, 310003, China. dorhushaohua@zju.edu.cn.; Brain Research Institute of Zhejiang University, Hangzhou, 310003, China. dorhushaohua@zju.edu.cn.; Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou, 310003, China. dorhushaohua@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, 15224, USA. shy229@pitt.edu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41380-026-03730-0
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            – D: 01
              M: 07
              Text: 2026 Jul 01
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