Phase 2 dose-expansion trial of OBI-3424, a DNA-alkylating prodrug, in patients with advanced solid tumors expressing AKR1C3.

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Bibliographic Details
Title: Phase 2 dose-expansion trial of OBI-3424, a DNA-alkylating prodrug, in patients with advanced solid tumors expressing AKR1C3.
Authors: Tsimberidou AM; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Verschraegen C; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, United States., Sigal D; Scripps Clinic and Scripps Cancer Center, La Jolla, CA, United States., Lenz HJ; Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Hochster H; Rutgers Cancer Institute, New Brunswick, NJ, United States., Baysal MA; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Chakraborty A; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Lee I; OBI Pharma USA, Inc., San Diego, CA, United States., Ristoski K; OBI Pharma USA, Inc., San Diego, CA, United States., Xu D; OBI Pharma USA, Inc., San Diego, CA, United States.
Source: The oncologist [Oncologist] 2026 Jul 08; Vol. 31 (8).
Publication Type: Journal Article; Clinical Trial, Phase II
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1549-490X
DOI:10.1093/oncolo/oyag254