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Oxypaeoniflorin Ameliorates Titanium Particle-Stimulated Osteolysis by Targeting Nrf2 to Reprogram Mitochondrial Homeostasis in Osteoclasts.

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Title: Oxypaeoniflorin Ameliorates Titanium Particle-Stimulated Osteolysis by Targeting Nrf2 to Reprogram Mitochondrial Homeostasis in Osteoclasts.
Authors: Zhu F; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China., Wu Z; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China., Hei J; Department of Orthopedics, The Chuzhou Hospital Affiliated With Anhui Medical University, Chuzhou, China., Tao H; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.; Department of Orthopedics Surgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, Jiangsu Province, China., Li W; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China., Chen K; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.; Department of Orthopedics, Hai'an People's Hospital, Jiangsu, China., Wang Q; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China., Geng D; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China., Wang Z; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China., Xu Y; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China., Lv S; Department of Orthopedics, Hai'an People's Hospital, Jiangsu, China.
Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2026 Jul; Vol. 30 (13), pp. e71266.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Oxypaeoniflorin Ameliorates Titanium Particle-Stimulated Osteolysis by Targeting Nrf2 to Reprogram Mitochondrial Homeostasis in Osteoclasts.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+F%22">Zhu F</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Wu+Z%22">Wu Z</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Hei+J%22">Hei J</searchLink>; Department of Orthopedics, The Chuzhou Hospital Affiliated With Anhui Medical University, Chuzhou, China.<br /><searchLink fieldCode="AU" term="%22Tao+H%22">Tao H</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.; Department of Orthopedics Surgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, Jiangsu Province, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.; Department of Orthopedics, Hai'an People's Hospital, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Geng+D%22">Geng D</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Orthopedics, The First Affiliated Hospital of Soochow University; Orthopedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Lv+S%22">Lv S</searchLink>; Department of Orthopedics, Hai'an People's Hospital, Jiangsu, China.
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              M: 07
              Text: 2026 Jul
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