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Implantable Cardioverter-Defibrillator Therapy in Contemporary Heart Failure Patients: An Analysis From the EMPEROR-Reduced Trial.

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Title: Implantable Cardioverter-Defibrillator Therapy in Contemporary Heart Failure Patients: An Analysis From the EMPEROR-Reduced Trial.
Authors: Aktaş MK; Clinical Cardiovascular Research Center, University of Rochester, Rochester, New York, USA. Electronic address: Mehmet_Aktas@urmc.rochester.edu., Talha KM; Department of Cardiovascular Disease, Loyola University Medical Center, Maywood, Illinois, USA., Goldenberg I; Clinical Cardiovascular Research Center, University of Rochester, Rochester, New York, USA., Zareba W; Clinical Cardiovascular Research Center, University of Rochester, Rochester, New York, USA., Böhm M; Departments of Internal Medicine and Cardiology, Angiology and Intensive Care Medicine, Saarland University, Saarbrücken, Germany., Abdin A; Departments of Internal Medicine and Cardiology, Angiology and Intensive Care Medicine, Saarland University, Saarbrücken, Germany., Brueckmann M; Boehringer Ingelheim International GmbH, Ingelheim, Germany; First Department of Medicine, Faculty of Medicine Mannheim, University of Heidelberg, Mannheim, Germany., Zeller C; Boehringer Ingelheim International GmbH, Ingelheim, Germany., Zaremba-Pechmann L; Elderbrook Solutions, Krakow, Poland., Pocock S; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, United Kingdom., Zannad F; Centre d'Investigations Cliniques Plurithématique 1433, Université de Lorraine, Institut National de la Santé et de la Recherche Médicale 1116, Centre Hospitalier Régional Universitaire de Nancy, French Clinical Research Infrastructure Network, Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Nancy, France., Anker SD; Department of Cardiology (CVK) of German Heart Center Charité, German Centre for Cardiovascular Research (DZHK), Charité Universitätsmedizin, Berlin, Germany., Filippatos G; National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece., Butler J; Department of Medicine, University of Mississippi, Jackson, Mississippi, USA; Baylor Scott and White Research Institute, Dallas, Texas, USA., Ferreira JP; Centre d'Investigations Cliniques Plurithématique 1433, Université de Lorraine, Institut National de la Santé et de la Recherche Médicale 1116, Centre Hospitalier Régional Universitaire de Nancy, French Clinical Research Infrastructure Network, Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Nancy, France; Cardiovascular R&D Center, Faculty of Medicine, University of Porto, Porto, Portugal; Heart Failure Clinic, Internal Medicine Department, Hospital de Gaia/Espinho, Gaia, Portugal., Packer M; Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas, USA.
Source: JACC. Heart failure [JACC Heart Fail] 2026 Jul 01, pp. 103166. Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101598241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-1787 (Electronic) Linking ISSN: 22131779 NLM ISO Abbreviation: JACC Heart Fail Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Aktaş+MK%22">Aktaş MK</searchLink>; Clinical Cardiovascular Research Center, University of Rochester, Rochester, New York, USA. Electronic address: Mehmet_Aktas@urmc.rochester.edu.<br /><searchLink fieldCode="AU" term="%22Talha+KM%22">Talha KM</searchLink>; Department of Cardiovascular Disease, Loyola University Medical Center, Maywood, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Goldenberg+I%22">Goldenberg I</searchLink>; Clinical Cardiovascular Research Center, University of Rochester, Rochester, New York, USA.<br /><searchLink fieldCode="AU" term="%22Zareba+W%22">Zareba W</searchLink>; Clinical Cardiovascular Research Center, University of Rochester, Rochester, New York, USA.<br /><searchLink fieldCode="AU" term="%22Böhm+M%22">Böhm M</searchLink>; Departments of Internal Medicine and Cardiology, Angiology and Intensive Care Medicine, Saarland University, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Abdin+A%22">Abdin A</searchLink>; Departments of Internal Medicine and Cardiology, Angiology and Intensive Care Medicine, Saarland University, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Brueckmann+M%22">Brueckmann M</searchLink>; Boehringer Ingelheim International GmbH, Ingelheim, Germany; First Department of Medicine, Faculty of Medicine Mannheim, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Zeller+C%22">Zeller C</searchLink>; Boehringer Ingelheim International GmbH, Ingelheim, Germany.<br /><searchLink fieldCode="AU" term="%22Zaremba-Pechmann+L%22">Zaremba-Pechmann L</searchLink>; Elderbrook Solutions, Krakow, Poland.<br /><searchLink fieldCode="AU" term="%22Pocock+S%22">Pocock S</searchLink>; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zannad+F%22">Zannad F</searchLink>; Centre d'Investigations Cliniques Plurithématique 1433, Université de Lorraine, Institut National de la Santé et de la Recherche Médicale 1116, Centre Hospitalier Régional Universitaire de Nancy, French Clinical Research Infrastructure Network, Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Anker+SD%22">Anker SD</searchLink>; Department of Cardiology (CVK) of German Heart Center Charité, German Centre for Cardiovascular Research (DZHK), Charité Universitätsmedizin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Filippatos+G%22">Filippatos G</searchLink>; National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Butler+J%22">Butler J</searchLink>; Department of Medicine, University of Mississippi, Jackson, Mississippi, USA; Baylor Scott and White Research Institute, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Ferreira+JP%22">Ferreira JP</searchLink>; Centre d'Investigations Cliniques Plurithématique 1433, Université de Lorraine, Institut National de la Santé et de la Recherche Médicale 1116, Centre Hospitalier Régional Universitaire de Nancy, French Clinical Research Infrastructure Network, Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Nancy, France; Cardiovascular R&D Center, Faculty of Medicine, University of Porto, Porto, Portugal; Heart Failure Clinic, Internal Medicine Department, Hospital de Gaia/Espinho, Gaia, Portugal.<br /><searchLink fieldCode="AU" term="%22Packer+M%22">Packer M</searchLink>; Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas, USA.
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