A Stepped Care, Peer-Delivered Intervention to Improve Substance Use and HIV Medication Adherence in Primary Care in South Africa (Project Khanya): Protocol for a Hybrid Type 2 Effectiveness-Implementation Randomized Controlled Trial.
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| Title: | A Stepped Care, Peer-Delivered Intervention to Improve Substance Use and HIV Medication Adherence in Primary Care in South Africa (Project Khanya): Protocol for a Hybrid Type 2 Effectiveness-Implementation Randomized Controlled Trial. |
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| Authors: | Magidson JF; Department of Psychology, University of Maryland, College Park, College Park, MD, United States.; Center for Substance Use, Addiction and Health Research (CESAR), University of Maryland, College Park, College Park, MD, 20742, United States, 1 301-405-5095., Hines AC; Center for Substance Use, Addiction and Health Research (CESAR), University of Maryland, College Park, College Park, MD, 20742, United States, 1 301-405-5095., Majokweni SH; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa., Tokwe L; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa., Myers B; Curtin enAble Institute, Faculty of Health Sciences, Curtin University, Bentley, Western Australia, Australia.; Mental Health, Alcohol, Substance Use, and Tobacco Research Unit, South African Medical Research Council, Cape Town, Western Cape, South Africa.; West Australian Country Health Service and Curtin University Research and Innovation Alliance, Perth, Western Australia, Australia., Du Toit S; Institute for Life Course Health Research, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, Western Cape, South Africa., Regenauer K; Department of Psychology, University of Maryland, College Park, College Park, MD, United States.; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States., Andersen LS; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.; Global Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Burnhams W; City of Cape Town Health and Substance Abuse, Cape Town, Western Cape, South Africa., Orrell C; HIV and Other Infectious Diseases Unit, South African Medical Research Council, Cape Town, Western Cape, South Africa.; Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa., Murphy SM; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States., Sibeko G; Division of Addiction Psychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa., Triplett N; Department of Psychology, University of Maryland, College Park, College Park, MD, United States., Ndwandwa E; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa., Kotelo NN; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa., Ma T; Department of Epidemiology and Biostatistics, University of Maryland, College Park, Maryland, MD, United States., Safren S; Department of Psychology, University of Miami, Miami, FL, United States., Joska J; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa. |
| Source: | JMIR research protocols [JMIR Res Protoc] 2026 Jul 02; Vol. 15, pp. e94153. Date of Electronic Publication: 2026 Jul 02. |
| Publication Type: | Clinical Trial Protocol; Journal Article |
| Journal Info: | Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101599504 Publication Model: Electronic Cited Medium: Internet ISSN: 1929-0748 (Electronic) Linking ISSN: 19290748 NLM ISO Abbreviation: JMIR Res Protoc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42390468 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A Stepped Care, Peer-Delivered Intervention to Improve Substance Use and HIV Medication Adherence in Primary Care in South Africa (Project Khanya): Protocol for a Hybrid Type 2 Effectiveness-Implementation Randomized Controlled Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Magidson+JF%22">Magidson JF</searchLink>; Department of Psychology, University of Maryland, College Park, College Park, MD, United States.; Center for Substance Use, Addiction and Health Research (CESAR), University of Maryland, College Park, College Park, MD, 20742, United States, 1 301-405-5095.<br /><searchLink fieldCode="AU" term="%22Hines+AC%22">Hines AC</searchLink>; Center for Substance Use, Addiction and Health Research (CESAR), University of Maryland, College Park, College Park, MD, 20742, United States, 1 301-405-5095.<br /><searchLink fieldCode="AU" term="%22Majokweni+SH%22">Majokweni SH</searchLink>; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Tokwe+L%22">Tokwe L</searchLink>; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Myers+B%22">Myers B</searchLink>; Curtin enAble Institute, Faculty of Health Sciences, Curtin University, Bentley, Western Australia, Australia.; Mental Health, Alcohol, Substance Use, and Tobacco Research Unit, South African Medical Research Council, Cape Town, Western Cape, South Africa.; West Australian Country Health Service and Curtin University Research and Innovation Alliance, Perth, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Du+Toit+S%22">Du Toit S</searchLink>; Institute for Life Course Health Research, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, Western Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Regenauer+K%22">Regenauer K</searchLink>; Department of Psychology, University of Maryland, College Park, College Park, MD, United States.; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Andersen+LS%22">Andersen LS</searchLink>; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.; Global Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Burnhams+W%22">Burnhams W</searchLink>; City of Cape Town Health and Substance Abuse, Cape Town, Western Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Orrell+C%22">Orrell C</searchLink>; HIV and Other Infectious Diseases Unit, South African Medical Research Council, Cape Town, Western Cape, South Africa.; Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Murphy+SM%22">Murphy SM</searchLink>; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Sibeko+G%22">Sibeko G</searchLink>; Division of Addiction Psychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Triplett+N%22">Triplett N</searchLink>; Department of Psychology, University of Maryland, College Park, College Park, MD, United States.<br /><searchLink fieldCode="AU" term="%22Ndwandwa+E%22">Ndwandwa E</searchLink>; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Kotelo+NN%22">Kotelo NN</searchLink>; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Ma+T%22">Ma T</searchLink>; Department of Epidemiology and Biostatistics, University of Maryland, College Park, Maryland, MD, United States.<br /><searchLink fieldCode="AU" term="%22Safren+S%22">Safren S</searchLink>; Department of Psychology, University of Miami, Miami, FL, United States.<br /><searchLink fieldCode="AU" term="%22Joska+J%22">Joska J</searchLink>; HIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101599504%22">JMIR research protocols</searchLink> [JMIR Res Protoc] 2026 Jul 02; Vol. 15, pp. e94153. <i>Date of Electronic Publication: </i>2026 Jul 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial Protocol; Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22JMIR+Publications%22">JMIR Publications </searchLink><i>Country of Publication: </i>Canada <i>NLM ID: </i>101599504 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1929-0748 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219290748%22">19290748 </searchLink><i>NLM ISO Abbreviation: </i>JMIR Res Protoc <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42390468 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.2196/94153 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e94153 Titles: – TitleFull: A Stepped Care, Peer-Delivered Intervention to Improve Substance Use and HIV Medication Adherence in Primary Care in South Africa (Project Khanya): Protocol for a Hybrid Type 2 Effectiveness-Implementation Randomized Controlled Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Magidson JF – PersonEntity: Name: NameFull: Hines AC – PersonEntity: Name: NameFull: Majokweni SH – PersonEntity: Name: NameFull: Tokwe L – PersonEntity: Name: NameFull: Myers B – PersonEntity: Name: NameFull: Du Toit S – PersonEntity: Name: NameFull: Regenauer K – PersonEntity: Name: NameFull: Andersen LS – PersonEntity: Name: NameFull: Burnhams W – PersonEntity: Name: NameFull: Orrell C – PersonEntity: Name: NameFull: Murphy SM – PersonEntity: Name: NameFull: Sibeko G – PersonEntity: Name: NameFull: Triplett N – PersonEntity: Name: NameFull: Ndwandwa E – PersonEntity: Name: NameFull: Kotelo NN – PersonEntity: Name: NameFull: Ma T – PersonEntity: Name: NameFull: Safren S – PersonEntity: Name: NameFull: Joska J IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 07 Text: 2026 Jul 02 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1929-0748 Numbering: – Type: volume Value: 15 Titles: – TitleFull: JMIR research protocols Type: main |
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