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An MR1-specific nanobody capable of blocking MR1T cell activation.

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Title: An MR1-specific nanobody capable of blocking MR1T cell activation.
Authors: Bates TA; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States., Kulicke CA; Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University, Portland, OR, United States., Gurmessa SK; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States., Kim SJ; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.; Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University, Portland, OR, United States.; Medical Scientist Training Program, Oregon Health & Science University, Portland, OR, United States., Suresh S; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada., Reyes-Weinstein JB; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States., Hinchliff A; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States., Burke JE; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada., Lewinsohn DM; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.; Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University, Portland, OR, United States.; Department of Pulmonary Medicine, VA Portland Health Care System, Research and Development, Portland, OR, United States.; Department of Pediatrics, Oregon Health and Science University, Portland, OR, United States., Tafesse FG; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, OR, United States.
Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2026 Jun 07; Vol. 215 (6).
Publication Type: Journal Article
Journal Info: Publisher: American Association of Immunologists Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An MR1-specific nanobody capable of blocking MR1T cell activation.
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  Data: <searchLink fieldCode="AU" term="%22Bates+TA%22">Bates TA</searchLink>; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.<br /><searchLink fieldCode="AU" term="%22Kulicke+CA%22">Kulicke CA</searchLink>; Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University, Portland, OR, United States.<br /><searchLink fieldCode="AU" term="%22Gurmessa+SK%22">Gurmessa SK</searchLink>; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.<br /><searchLink fieldCode="AU" term="%22Kim+SJ%22">Kim SJ</searchLink>; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.; Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University, Portland, OR, United States.; Medical Scientist Training Program, Oregon Health & Science University, Portland, OR, United States.<br /><searchLink fieldCode="AU" term="%22Suresh+S%22">Suresh S</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Reyes-Weinstein+JB%22">Reyes-Weinstein JB</searchLink>; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.<br /><searchLink fieldCode="AU" term="%22Hinchliff+A%22">Hinchliff A</searchLink>; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.<br /><searchLink fieldCode="AU" term="%22Burke+JE%22">Burke JE</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Lewinsohn+DM%22">Lewinsohn DM</searchLink>; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.; Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University, Portland, OR, United States.; Department of Pulmonary Medicine, VA Portland Health Care System, Research and Development, Portland, OR, United States.; Department of Pediatrics, Oregon Health and Science University, Portland, OR, United States.<br /><searchLink fieldCode="AU" term="%22Tafesse+FG%22">Tafesse FG</searchLink>; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, United States.; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, OR, United States.
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  Data: <searchLink fieldCode="JN" term="%222985117R%22">Journal of immunology (Baltimore, Md. : 1950)</searchLink> [J Immunol] 2026 Jun 07; Vol. 215 (6).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+of+Immunologists%22">American Association of Immunologists </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985117R <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1550-6606 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221767%22">00221767 </searchLink><i>NLM ISO Abbreviation: </i>J Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.1093/jimmun/vkag094
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        Text: English
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            – D: 07
              M: 06
              Text: 2026 Jun 07
              Type: published
              Y: 2026
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