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CBFβ-SMMHC in inv(16) AML: Fusion biology, RUNX1 dysregulation, and therapeutic targeting of a leukemogenic protein-protein interaction.

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Title: CBFβ-SMMHC in inv(16) AML: Fusion biology, RUNX1 dysregulation, and therapeutic targeting of a leukemogenic protein-protein interaction.
Authors: Kamel EM; Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef 62514, Egypt., Khadrawy SM; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia., Ali MAM; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia., Ahmed NA; Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, P.O. Box 62521, Beni-Suef, Egypt. Electronic address: drnohascience@science.bsu.edu.eg., Alkhedhairi S; Department of Medical Biosciences, College of Veterinary Medicine, Qassim University, P.O. Box 6622, Buraydah 51452, Saudi Arabia., Aba Alkhayl FF; Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia., Lamsabhi AM; Departamento de Química and Institute for advanced research in chemical Science (IAdChem), Facultad de Ciencias, Universidad Autónoma de Madrid, Módulo 13, Madrid 28049, Spain.
Source: Pathology, research and practice [Pathol Res Pract] 2026 Jul 01; Vol. 286, pp. 156607. Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article; Review
Journal Info: Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0631 (Electronic) Linking ISSN: 03440338 NLM ISO Abbreviation: Pathol Res Pract Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CBFβ-SMMHC in inv(16) AML: Fusion biology, RUNX1 dysregulation, and therapeutic targeting of a leukemogenic protein-protein interaction.
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  Data: <searchLink fieldCode="AU" term="%22Kamel+EM%22">Kamel EM</searchLink>; Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef 62514, Egypt.<br /><searchLink fieldCode="AU" term="%22Khadrawy+SM%22">Khadrawy SM</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ali+MAM%22">Ali MAM</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ahmed+NA%22">Ahmed NA</searchLink>; Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, P.O. Box 62521, Beni-Suef, Egypt. Electronic address: drnohascience@science.bsu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Alkhedhairi+S%22">Alkhedhairi S</searchLink>; Department of Medical Biosciences, College of Veterinary Medicine, Qassim University, P.O. Box 6622, Buraydah 51452, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aba+Alkhayl+FF%22">Aba Alkhayl FF</searchLink>; Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Lamsabhi+AM%22">Lamsabhi AM</searchLink>; Departamento de Química and Institute for advanced research in chemical Science (IAdChem), Facultad de Ciencias, Universidad Autónoma de Madrid, Módulo 13, Madrid 28049, Spain.
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  Data: <searchLink fieldCode="JN" term="%227806109%22">Pathology, research and practice</searchLink> [Pathol Res Pract] 2026 Jul 01; Vol. 286, pp. 156607. <i>Date of Electronic Publication: </i>2026 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Gustav+Fischer+Verlag%22">Gustav Fischer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>7806109 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1618-0631 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203440338%22">03440338 </searchLink><i>NLM ISO Abbreviation: </i>Pathol Res Pract <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.prp.2026.156607
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        Text: English
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      – TitleFull: CBFβ-SMMHC in inv(16) AML: Fusion biology, RUNX1 dysregulation, and therapeutic targeting of a leukemogenic protein-protein interaction.
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              Text: 2026 Jul 01
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