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Differential perforin sensitivity drives lineage-dependent resistance to CAR T-cell killing in blood cancer cell lines.

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Title: Differential perforin sensitivity drives lineage-dependent resistance to CAR T-cell killing in blood cancer cell lines.
Authors: Hodel AW; Peter MacCallum Cancer Centre, Melbourne, Australia., Noori T; Peter MacCallum cancer centre, Melbourne, Australia., Rudd-Schmidt JA; Peter MacCallum Cancer Centre, Melbourne, Australia., Williams SA; Peter MacCallum Cancer Centre, Melbourne, Australia., Sutton VR; Peter MacCallum Cancer Centre, Melbourne, Australia., Hoogenboom BW; University College London, London, United Kingdom., Tam CS; Alfred Hospital and Monash University, East Melbourne, Australia., Trapani JA; Peter MacCallum Cancer Center, Melbourne, Australia., Voskoboinik I; Peter MacCallum Cancer Centre, Melbourne, Australia.
Source: Blood advances [Blood Adv] 2026 Jul 02. Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42392175
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Differential perforin sensitivity drives lineage-dependent resistance to CAR T-cell killing in blood cancer cell lines.
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  Data: <searchLink fieldCode="AU" term="%22Hodel+AW%22">Hodel AW</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Noori+T%22">Noori T</searchLink>; Peter MacCallum cancer centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Rudd-Schmidt+JA%22">Rudd-Schmidt JA</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Williams+SA%22">Williams SA</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Sutton+VR%22">Sutton VR</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Hoogenboom+BW%22">Hoogenboom BW</searchLink>; University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tam+CS%22">Tam CS</searchLink>; Alfred Hospital and Monash University, East Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Trapani+JA%22">Trapani JA</searchLink>; Peter MacCallum Cancer Center, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Voskoboinik+I%22">Voskoboinik I</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101698425%22">Blood advances</searchLink> [Blood Adv] 2026 Jul 02. <i>Date of Electronic Publication: </i>2026 Jul 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1182/bloodadvances.2026019881
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      – Code: eng
        Text: English
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      – TitleFull: Differential perforin sensitivity drives lineage-dependent resistance to CAR T-cell killing in blood cancer cell lines.
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            NameFull: Hodel AW
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            NameFull: Noori T
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            – D: 02
              M: 07
              Text: 2026 Jul 02
              Type: published
              Y: 2026
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            – Type: issn-electronic
              Value: 2473-9537
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            – TitleFull: Blood advances
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