Longitudinal analysis of drift in the circulating human antibody repertoire over four years.

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Title: Longitudinal analysis of drift in the circulating human antibody repertoire over four years.
Authors: Joyce C; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Nemoz B; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA, USA., Bastidas R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Briney B; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. briney@scripps.edu.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA, USA. briney@scripps.edu.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA, USA. briney@scripps.edu.; Multi-Omics Vaccine Evaluation (MOVE) Consortium, The Scripps Research Institute, La Jolla, CA, USA. briney@scripps.edu., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. burton@scripps.edu.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA, USA. burton@scripps.edu.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA. burton@scripps.edu.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. burton@scripps.edu.
Source: Scientific reports [Sci Rep] 2026 Jul 02. Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-60159-9