Metabolomic Network Analysis Reveals Reorganization of Lipid and Steroid Programs Linked to Right Ventricular-Pulmonary Vascular Function in Pulmonary Hypertension.

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Title: Metabolomic Network Analysis Reveals Reorganization of Lipid and Steroid Programs Linked to Right Ventricular-Pulmonary Vascular Function in Pulmonary Hypertension.
Authors: Clinton IW; Division of Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Coursen JC; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Rosen DT; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Suresh K; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Balasubramanian A; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Kolb TM; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Damico RL; Division of Pulmonary, Critical Care, and Sleep Medicine University of Miami, FL., Mathai SC; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Hsu S; Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD., Mukherjee M; Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD., Finet JE; Department of Cardiovascular Medicine, Cleveland Clinic, OH., Grunig G; Department of Medicine, New York University Grossman School of Medicine, New York, NY., Barnard J; Department of Quantitative Health Sciences, Cleveland Clinic, OH., Hemnes AR; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN., Leopold JA; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Horn EM; Perkin Heart Failure Center, Division of Cardiology, Weill Cornell Medicine, New York, NY., Rosenzweig EB; Department of Pediatrics, Westchester Medical Center, New York Medical College, Valhalla, NY., Rischard F; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Arizona, Tucson., Frantz RP; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Erzurum SC; Lerner Research Institute, Cleveland Clinic, OH., King W; Lerner Research Institute, Cleveland Clinic, OH., Beck GJ; Lerner Research Institute, Cleveland Clinic, OH., Hill NS; Division of Pulmonary, Critical Care, and Sleep Medicine, Tufts Medical Center, Boston, MA., Hassoun PM; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Simpson CE; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 22. Date of Electronic Publication: 2026 Jun 22.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Metabolomic Network Analysis Reveals Reorganization of Lipid and Steroid Programs Linked to Right Ventricular-Pulmonary Vascular Function in Pulmonary Hypertension.
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  Data: <searchLink fieldCode="AU" term="%22Clinton+IW%22">Clinton IW</searchLink>; Division of Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Coursen+JC%22">Coursen JC</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Rosen+DT%22">Rosen DT</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Suresh+K%22">Suresh K</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Balasubramanian+A%22">Balasubramanian A</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Kolb+TM%22">Kolb TM</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Damico+RL%22">Damico RL</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine University of Miami, FL.<br /><searchLink fieldCode="AU" term="%22Mathai+SC%22">Mathai SC</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Hsu+S%22">Hsu S</searchLink>; Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Mukherjee+M%22">Mukherjee M</searchLink>; Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Finet+JE%22">Finet JE</searchLink>; Department of Cardiovascular Medicine, Cleveland Clinic, OH.<br /><searchLink fieldCode="AU" term="%22Grunig+G%22">Grunig G</searchLink>; Department of Medicine, New York University Grossman School of Medicine, New York, NY.<br /><searchLink fieldCode="AU" term="%22Barnard+J%22">Barnard J</searchLink>; Department of Quantitative Health Sciences, Cleveland Clinic, OH.<br /><searchLink fieldCode="AU" term="%22Hemnes+AR%22">Hemnes AR</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Leopold+JA%22">Leopold JA</searchLink>; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Horn+EM%22">Horn EM</searchLink>; Perkin Heart Failure Center, Division of Cardiology, Weill Cornell Medicine, New York, NY.<br /><searchLink fieldCode="AU" term="%22Rosenzweig+EB%22">Rosenzweig EB</searchLink>; Department of Pediatrics, Westchester Medical Center, New York Medical College, Valhalla, NY.<br /><searchLink fieldCode="AU" term="%22Rischard+F%22">Rischard F</searchLink>; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Arizona, Tucson.<br /><searchLink fieldCode="AU" term="%22Frantz+RP%22">Frantz RP</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.<br /><searchLink fieldCode="AU" term="%22Erzurum+SC%22">Erzurum SC</searchLink>; Lerner Research Institute, Cleveland Clinic, OH.<br /><searchLink fieldCode="AU" term="%22King+W%22">King W</searchLink>; Lerner Research Institute, Cleveland Clinic, OH.<br /><searchLink fieldCode="AU" term="%22Beck+GJ%22">Beck GJ</searchLink>; Lerner Research Institute, Cleveland Clinic, OH.<br /><searchLink fieldCode="AU" term="%22Hill+NS%22">Hill NS</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine, Tufts Medical Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Hassoun+PM%22">Hassoun PM</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Simpson+CE%22">Simpson CE</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Jun 22. <i>Date of Electronic Publication: </i>2026 Jun 22.
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        Value: 10.64898/2026.06.16.732773
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