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Favipiravir tissue distribution and inhibitory quotients in preclinical models: towards a pipeline for evidence-based antiviral repurposing.

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Title: Favipiravir tissue distribution and inhibitory quotients in preclinical models: towards a pipeline for evidence-based antiviral repurposing.
Authors: Petit PR; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France., Touret F; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France., Driouich JS; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France., Paré A; Unité Toxicologie ExpérimentAle et Modélisation, INERIS, Institut National de L'Environnement Industriel et des Risques, Verneuil-en-Halatte 60550, France., de Lamballerie X; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France., Marlin R; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France., Contreras V; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France., Relouzat F; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France., Gallouët AS; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France., Pascal Q; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France., Guedj J; Université de Paris, INSERM, IAME, Paris F-75018, France., Le Grand R; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France., Nougairède A; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France., Solas C; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France.; Laboratoire de Pharmacocinétique et Toxicologie, Hôpital La Timone, APHM, Marseille, France.
Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2026 Jul 02; Vol. 81 (8).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Petit+PR%22">Petit PR</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France.<br /><searchLink fieldCode="AU" term="%22Touret+F%22">Touret F</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France.<br /><searchLink fieldCode="AU" term="%22Driouich+JS%22">Driouich JS</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France.<br /><searchLink fieldCode="AU" term="%22Paré+A%22">Paré A</searchLink>; Unité Toxicologie ExpérimentAle et Modélisation, INERIS, Institut National de L'Environnement Industriel et des Risques, Verneuil-en-Halatte 60550, France.<br /><searchLink fieldCode="AU" term="%22de+Lamballerie+X%22">de Lamballerie X</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France.<br /><searchLink fieldCode="AU" term="%22Marlin+R%22">Marlin R</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Contreras+V%22">Contreras V</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Relouzat+F%22">Relouzat F</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Gallouët+AS%22">Gallouët AS</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Pascal+Q%22">Pascal Q</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Guedj+J%22">Guedj J</searchLink>; Université de Paris, INSERM, IAME, Paris F-75018, France.<br /><searchLink fieldCode="AU" term="%22Le+Grand+R%22">Le Grand R</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases » (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Nougairède+A%22">Nougairède A</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France.<br /><searchLink fieldCode="AU" term="%22Solas+C%22">Solas C</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille 13005, France.; Laboratoire de Pharmacocinétique et Toxicologie, Hôpital La Timone, APHM, Marseille, France.
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