Real-time transcriptomic profiling of hPSC-derived cartilage during development identifies a key role for the extracellular matrix in homeostasis and protection.

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Title: Real-time transcriptomic profiling of hPSC-derived cartilage during development identifies a key role for the extracellular matrix in homeostasis and protection.
Authors: Raftery RM; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02115, USA.; Department of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork TF12XF62, Ireland.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA., Pregizer SK; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02115, USA., Raj S; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Venkatasubramanian D; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Alemany-Ribes M; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02115, USA., Craft AM; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
Source: Development (Cambridge, England) [Development] 2026 Aug 15; Vol. 153 (16). Date of Electronic Publication: 2026 Jul 03.
Publication Type: Journal Article
Journal Info: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Raftery+RM%22">Raftery RM</searchLink>; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02115, USA.; Department of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork TF12XF62, Ireland.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA.<br /><searchLink fieldCode="AU" term="%22Pregizer+SK%22">Pregizer SK</searchLink>; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Raj+S%22">Raj S</searchLink>; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Venkatasubramanian+D%22">Venkatasubramanian D</searchLink>; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Alemany-Ribes+M%22">Alemany-Ribes M</searchLink>; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Craft+AM%22">Craft AM</searchLink>; Department of Orthopedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
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        Value: 10.1242/dev.205520
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      – TitleFull: Real-time transcriptomic profiling of hPSC-derived cartilage during development identifies a key role for the extracellular matrix in homeostasis and protection.
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              Text: 2026 Aug 15
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