Optimizing the Stupp protocol for treatment of glioblastoma: eliminating age bias, enhancing treatment timing, use of stereotactically-guided sequential boost, and dexamethasone dosing.

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Title: Optimizing the Stupp protocol for treatment of glioblastoma: eliminating age bias, enhancing treatment timing, use of stereotactically-guided sequential boost, and dexamethasone dosing.
Authors: Sharpe MA; Kenneth R. Peak Brain and Pituitary Treatment Center, Houston Methodist Hospital, Houston, TX, USA.; Department of Neurosurgery, Houston Methodist Hospital, Houston, TX, USA.; Houston Methodist Research Institute, Houston, TX, USA., Baskin AM; Kenneth R. Peak Brain and Pituitary Treatment Center, Houston Methodist Hospital, Houston, TX, USA.; Department of Neurosurgery, Houston Methodist Hospital, Houston, TX, USA.; Houston Methodist Research Institute, Houston, TX, USA., Teh BS; Houston Methodist Research Institute, Houston, TX, USA.; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, USA.; Weill Cornell Medical College, New York, NY, USA.; Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX, USA., Butler EB; Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, USA., Baskin DS; Kenneth R. Peak Brain and Pituitary Treatment Center, Houston Methodist Hospital, Houston, TX, USA. dbaskin@houstonmethodist.org.; Department of Neurosurgery, Houston Methodist Hospital, Houston, TX, USA. dbaskin@houstonmethodist.org.; Houston Methodist Research Institute, Houston, TX, USA. dbaskin@houstonmethodist.org.; Weill Cornell Medical College, New York, NY, USA. dbaskin@houstonmethodist.org.; Naresh K. Vashisht College of Medicine, Texas A&M University, Bryan, TX, USA. dbaskin@houstonmethodist.org.; Department of Neurosurgery, 6445 Main Street, Outpatient Center, Floor 24, Houston, TX, 77030, USA. dbaskin@houstonmethodist.org.
Source: Journal of neuro-oncology [J Neurooncol] 2026 Jul 03; Vol. 178 (3). Date of Electronic Publication: 2026 Jul 03.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-7373
DOI:10.1007/s11060-026-05685-2