A calreticulin-linked HPV-16 E7 minigene DNA vaccine elicits strong E7-specific CD8+ T-cell immunity and durable antitumor effects in a preclinical model.
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| Title: | A calreticulin-linked HPV-16 E7 minigene DNA vaccine elicits strong E7-specific CD8+ T-cell immunity and durable antitumor effects in a preclinical model. |
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| Authors: | Chang YC; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA., Xu Y; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA., Tsai YC; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA., Yu CW; Department of Medicine, MacKay Medical University, New Taipei City, Taiwan., Chang CL; Department of Obstetrics and Gynecology, MacKay Memorial Hospital, Taipei, 104217, Taiwan., Huang CH; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA.; Department of Cell Biology, Johns Hopkins University, Baltimore, MD, 21287, USA., Wu TC; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA. wutc@jhmi.edu.; Department of Oncology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA. wutc@jhmi.edu.; Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. wutc@jhmi.edu.; Molecular Microbiology and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. wutc@jhmi.edu., Hung CF; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA. chung2@jhmi.edu.; Department of Oncology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA. chung2@jhmi.edu. |
| Source: | Scientific reports [Sci Rep] 2026 Jul 03. Date of Electronic Publication: 2026 Jul 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42399330 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A calreticulin-linked HPV-16 E7 minigene DNA vaccine elicits strong E7-specific CD8+ T-cell immunity and durable antitumor effects in a preclinical model. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chang+YC%22">Chang YC</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA.<br /><searchLink fieldCode="AU" term="%22Tsai+YC%22">Tsai YC</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA.<br /><searchLink fieldCode="AU" term="%22Yu+CW%22">Yu CW</searchLink>; Department of Medicine, MacKay Medical University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CL%22">Chang CL</searchLink>; Department of Obstetrics and Gynecology, MacKay Memorial Hospital, Taipei, 104217, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CH%22">Huang CH</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA.; Department of Cell Biology, Johns Hopkins University, Baltimore, MD, 21287, USA.<br /><searchLink fieldCode="AU" term="%22Wu+TC%22">Wu TC</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA. wutc@jhmi.edu.; Department of Oncology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA. wutc@jhmi.edu.; Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. wutc@jhmi.edu.; Molecular Microbiology and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. wutc@jhmi.edu.<br /><searchLink fieldCode="AU" term="%22Hung+CF%22">Hung CF</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA. chung2@jhmi.edu.; Department of Oncology, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB II 307, Baltimore, MD, 21287, USA. chung2@jhmi.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Jul 03. <i>Date of Electronic Publication: </i>2026 Jul 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42399330 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-026-58415-z Languages: – Code: eng Text: English Titles: – TitleFull: A calreticulin-linked HPV-16 E7 minigene DNA vaccine elicits strong E7-specific CD8+ T-cell immunity and durable antitumor effects in a preclinical model. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chang YC – PersonEntity: Name: NameFull: Xu Y – PersonEntity: Name: NameFull: Tsai YC – PersonEntity: Name: NameFull: Yu CW – PersonEntity: Name: NameFull: Chang CL – PersonEntity: Name: NameFull: Huang CH – PersonEntity: Name: NameFull: Wu TC – PersonEntity: Name: NameFull: Hung CF IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 07 Text: 2026 Jul 03 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2045-2322 Titles: – TitleFull: Scientific reports Type: main |
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