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Intraoperative dexmedetomidine reduces postoperative sleep disturbance in older adults undergoing major abdominal surgery: a single-center, randomized, double-blind, placebo-controlled trial.

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Title: Intraoperative dexmedetomidine reduces postoperative sleep disturbance in older adults undergoing major abdominal surgery: a single-center, randomized, double-blind, placebo-controlled trial.
Authors: Peng HP; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China., Hu JH; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China., Fan LP; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China.; Jintan Traditional Chinese Medicine Hospital, Changzhou, China., Yang X; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China., Liu HY; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China., Shan XS; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China., Liu H; Department of Anesthesiology and Pain Medicine, University of California Davis Health, Sacramento, CA, USA., Sudhan N; Anesthesia and Critical Care, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Trust, London, UK., Ji FH; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China. jifuhaisuda@163.com.; Institute of Anesthesiology, Soochow University, Suzhou, China. jifuhaisuda@163.com., Peng K; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China. pengke@suda.edu.cn.; Institute of Anesthesiology, Soochow University, Suzhou, China. pengke@suda.edu.cn.
Source: Communications medicine [Commun Med (Lond)] 2026 Jul 03. Date of Electronic Publication: 2026 Jul 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918250414506676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2730-664X (Electronic) Linking ISSN: 2730664X NLM ISO Abbreviation: Commun Med (Lond)
Database: MEDLINE Ultimate
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  Data: Intraoperative dexmedetomidine reduces postoperative sleep disturbance in older adults undergoing major abdominal surgery: a single-center, randomized, double-blind, placebo-controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Peng+HP%22">Peng HP</searchLink>; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Hu+JH%22">Hu JH</searchLink>; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Fan+LP%22">Fan LP</searchLink>; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China.; Jintan Traditional Chinese Medicine Hospital, Changzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+HY%22">Liu HY</searchLink>; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Shan+XS%22">Shan XS</searchLink>; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Anesthesiology, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Anesthesiology and Pain Medicine, University of California Davis Health, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sudhan+N%22">Sudhan N</searchLink>; Anesthesia and Critical Care, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Ji+FH%22">Ji FH</searchLink>; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China. jifuhaisuda@163.com.; Institute of Anesthesiology, Soochow University, Suzhou, China. jifuhaisuda@163.com.<br /><searchLink fieldCode="AU" term="%22Peng+K%22">Peng K</searchLink>; Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China. pengke@suda.edu.cn.; Institute of Anesthesiology, Soochow University, Suzhou, China. pengke@suda.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229918250414506676%22">Communications medicine</searchLink> [Commun Med (Lond)] 2026 Jul 03. <i>Date of Electronic Publication: </i>2026 Jul 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Portfolio%22">Nature Portfolio </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9918250414506676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2730-664X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222730664X%22">2730664X </searchLink><i>NLM ISO Abbreviation: </i>Commun Med (Lond)
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        Value: 10.1038/s43856-026-01769-2
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            – D: 03
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              Text: 2026 Jul 03
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