Silymarin Reverses Seizure-Precipitating Effects of Alcohol and Associated Psychiatric Comorbidities, and Neurotoxicity in Pentylenetetrazol Pre-Kindled Mice.

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Title: Silymarin Reverses Seizure-Precipitating Effects of Alcohol and Associated Psychiatric Comorbidities, and Neurotoxicity in Pentylenetetrazol Pre-Kindled Mice.
Authors: Ben-Azu B; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria. pharmben4ever@yahoo.com.; Research unit of Neuroinflammatory and Cardiovascular Pharmacology, Department of Animal Biology, Faculty of Sciences, University of Dschang, Dschang, Cameroon. pharmben4ever@yahoo.com., Omogbiya IA; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria., Emudainohwo JOT; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria., Fokoua AR; Research unit of Neuroinflammatory and Cardiovascular Pharmacology, Department of Animal Biology, Faculty of Sciences, University of Dschang, Dschang, Cameroon., Annafi OS; Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria., Chijioke BS; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria., Esuku DT; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria., Chidebe EO; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria., Oritsemuelebi B; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria., Oboh M; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria., Onoriadjeren WO; Department of Science Laboratory Technology, Delta State Polytechnic Otefe-Oghara, Otefe, Delta State, Nigeria., Nwangwa EK; Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.
Source: Neurotoxicity research [Neurotox Res] 2026 Jul 04; Vol. 44 (4). Date of Electronic Publication: 2026 Jul 04.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-3524 (Electronic) Linking ISSN: 10298428 NLM ISO Abbreviation: Neurotox Res Subsets: MEDLINE
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  Data: Silymarin Reverses Seizure-Precipitating Effects of Alcohol and Associated Psychiatric Comorbidities, and Neurotoxicity in Pentylenetetrazol Pre-Kindled Mice.
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  Data: <searchLink fieldCode="AU" term="%22Ben-Azu+B%22">Ben-Azu B</searchLink>; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria. pharmben4ever@yahoo.com.; Research unit of Neuroinflammatory and Cardiovascular Pharmacology, Department of Animal Biology, Faculty of Sciences, University of Dschang, Dschang, Cameroon. pharmben4ever@yahoo.com.<br /><searchLink fieldCode="AU" term="%22Omogbiya+IA%22">Omogbiya IA</searchLink>; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Emudainohwo+JOT%22">Emudainohwo JOT</searchLink>; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Fokoua+AR%22">Fokoua AR</searchLink>; Research unit of Neuroinflammatory and Cardiovascular Pharmacology, Department of Animal Biology, Faculty of Sciences, University of Dschang, Dschang, Cameroon.<br /><searchLink fieldCode="AU" term="%22Annafi+OS%22">Annafi OS</searchLink>; Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Chijioke+BS%22">Chijioke BS</searchLink>; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Esuku+DT%22">Esuku DT</searchLink>; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Chidebe+EO%22">Chidebe EO</searchLink>; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Oritsemuelebi+B%22">Oritsemuelebi B</searchLink>; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Oboh+M%22">Oboh M</searchLink>; DELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Onoriadjeren+WO%22">Onoriadjeren WO</searchLink>; Department of Science Laboratory Technology, Delta State Polytechnic Otefe-Oghara, Otefe, Delta State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Nwangwa+EK%22">Nwangwa EK</searchLink>; Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.
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  Data: <searchLink fieldCode="JN" term="%22100929017%22">Neurotoxicity research</searchLink> [Neurotox Res] 2026 Jul 04; Vol. 44 (4). <i>Date of Electronic Publication: </i>2026 Jul 04.
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      – TitleFull: Silymarin Reverses Seizure-Precipitating Effects of Alcohol and Associated Psychiatric Comorbidities, and Neurotoxicity in Pentylenetetrazol Pre-Kindled Mice.
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              Text: 2026 Jul 04
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