Generalizable AI predicts immunotherapy outcomes across cancers and treatments.

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Title: Generalizable AI predicts immunotherapy outcomes across cancers and treatments.
Authors: Shen W; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China., Moon I; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Nguyen TH; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Li MM; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Huang Y; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Nair N; Roche Pharma Research and Early Development, Oncology Early Clinical Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland., Marbach D; Computational Sciences Center of Excellence, F. Hoffmann-La Roche Ltd., Basel, Switzerland. daniel.marbach.dm1@roche.com., Zitnik M; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. marinka@hms.harvard.edu.; Kempner Institute for the Study of Natural and Artificial Intelligence, Harvard University, Allston, MA, USA. marinka@hms.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. marinka@hms.harvard.edu.; Harvard Data Science Initiative, Cambridge, MA, USA. marinka@hms.harvard.edu.
Source: Nature medicine [Nat Med] 2026 Jul 03. Date of Electronic Publication: 2026 Jul 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Shen+W%22">Shen W</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Moon+I%22">Moon I</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+TH%22">Nguyen TH</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Li+MM%22">Li MM</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nair+N%22">Nair N</searchLink>; Roche Pharma Research and Early Development, Oncology Early Clinical Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marbach+D%22">Marbach D</searchLink>; Computational Sciences Center of Excellence, F. Hoffmann-La Roche Ltd., Basel, Switzerland. daniel.marbach.dm1@roche.com.<br /><searchLink fieldCode="AU" term="%22Zitnik+M%22">Zitnik M</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. marinka@hms.harvard.edu.; Kempner Institute for the Study of Natural and Artificial Intelligence, Harvard University, Allston, MA, USA. marinka@hms.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. marinka@hms.harvard.edu.; Harvard Data Science Initiative, Cambridge, MA, USA. marinka@hms.harvard.edu.
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              Text: 2026 Jul 03
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