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Effects of quetiapine on cognitive functioning in schizophrenia: evidence for the remyelination hypothesis?

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Title: Effects of quetiapine on cognitive functioning in schizophrenia: evidence for the remyelination hypothesis?
Authors: Ising M; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany. ising@psych.mpg.de., Raabe F; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany.; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany., Fischer L; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany., Schmitt A; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Laboratory of Neuroscience (LIM27), Institute of Psychiatry, University of Sao Paulo, São Paulo, 05453-010, SP, Brazil.; German Center for Mental Health (DZPG), Partner site Munich-Augsburg, Munich, Germany., Sämann P; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany., Adorjan K; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland., Anghelescu IG; Department of Psychiatry and Psychotherapy, Mental Health Institute Berlin, 14050, Berlin, Germany., Arolt V; Institute for Translational Psychiatry, University of Münster, 48149, Münster, Germany., Baune BT; Department of Psychiatry, University of Münster, 48149, Münster, Germany.; Department of Psychiatry, Melbourne Medical School, The University of Melbourne, Melbourne, Australia.; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia., Dannlowski U; Institute for Translational Psychiatry, University of Münster, 48149, Münster, Germany.; Department of Psychiatry, Medical School, University Medical Center OWL, Protestant Hospital of the Bethel Foundation, Bielefeld University, Bielefeld, Germany.; German Center for Mental Health (DZPG), Site Jena Magdeburg Halle, Jena, Germany.; Center for Intervention and Research on Adaptive and Maladaptive Brain, Circuits Underlying Mental Health (C-I-R-C), Site Jena Magdeburg Halle, Jena, Germany., Dietrich DE; AMEOS Clinical Center Hildesheim, 31135, Hildesheim, Germany.; Center for Systems Neuroscience (ZSN), 30559, Hannover, Germany.; Department of Psychiatry, Medical School of Hannover, 30625, Hannover, Germany., Fallgatter AJ; Department of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), University of Tübingen, 72076, Tübingen, Germany.; German Center for Mental Health (DZPG), Partner Site Tübingen, 72076, Tübingen, Germany., Figge C; Karl-Jaspers Clinic, European Medical School Oldenburg-Groningen, 26160, Oldenburg, Germany., Heilbronner M; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany., Jäger M; Department of Psychiatry II, Ulm University, Bezirkskrankenhaus Günzburg, 89312, Günzburg, Germany., Juckel G; Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, 44791, Bochum, Germany., Konrad C; Department of Psychiatry and Psychotherapy, Agaplesion Diakonieklinikum, 27356, Rotenburg, Germany., Navarro-Flores A; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany., Kohshour MO; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Department of Immunology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Reich-Erkelenz D; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany., Reimer J; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.; Center for Psychosocial Medicine, Academic Teaching Hospital Itzehoe, Itzehoe, Germany., Reininghaus EZ; Division of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, 8036, Austria., Schmauß M; Clinic for Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, Augsburg University, Bezirkskrankenhaus Augsburg, 86156, Augsburg, Germany., Schulte EC; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.; German Center for Mental Health (DZPG), Partner site Munich-Augsburg, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Bonn, University of Bonn, 53127, Bonn, Germany.; Institute of Human Genetics, Faculty of Medicine and University Hospital Bonn, University of Bonn, Bonn, Germany., Senner F; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Centres for Psychiatry Suedwuerttemberg, 88214, Ravensburg, Germany., Spitzer C; Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Rostock, 18147, Rostock, Germany., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, 37075, Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), 37075, Göttingen, Germany.; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Aveiro, Portugal., Zimmermann J; Psychiatrieverbund Oldenburger Land gGmbH, Karl-Jaspers-Klinik, 26160, Bad Zwischenahn, Germany., Schulze TG; German Center for Mental Health (DZPG), Partner site Munich-Augsburg, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Heilbronner U; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany., Budde M; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany., Papiol S; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany., Falkai P; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany.; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.; German Center for Mental Health (DZPG), Partner site Munich-Augsburg, Munich, Germany.
Source: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2026 Jul 04. Date of Electronic Publication: 2026 Jul 04.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9103030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-8491 (Electronic) Linking ISSN: 09401334 NLM ISO Abbreviation: Eur Arch Psychiatry Clin Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effects of quetiapine on cognitive functioning in schizophrenia: evidence for the remyelination hypothesis?
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  Data: <searchLink fieldCode="AU" term="%22Ising+M%22">Ising M</searchLink>; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany. ising@psych.mpg.de.<br /><searchLink fieldCode="AU" term="%22Raabe+F%22">Raabe F</searchLink>; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany.; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+L%22">Fischer L</searchLink>; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schmitt+A%22">Schmitt A</searchLink>; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Laboratory of Neuroscience (LIM27), Institute of Psychiatry, University of Sao Paulo, São Paulo, 05453-010, SP, Brazil.; German Center for Mental Health (DZPG), Partner site Munich-Augsburg, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sämann+P%22">Sämann P</searchLink>; 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Institute for Translational Psychiatry, University of Münster, 48149, Münster, Germany.; Department of Psychiatry, Medical School, University Medical Center OWL, Protestant Hospital of the Bethel Foundation, Bielefeld University, Bielefeld, Germany.; German Center for Mental Health (DZPG), Site Jena Magdeburg Halle, Jena, Germany.; Center for Intervention and Research on Adaptive and Maladaptive Brain, Circuits Underlying Mental Health (C-I-R-C), Site Jena Magdeburg Halle, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Dietrich+DE%22">Dietrich DE</searchLink>; AMEOS Clinical Center Hildesheim, 31135, Hildesheim, Germany.; Center for Systems Neuroscience (ZSN), 30559, Hannover, Germany.; Department of Psychiatry, Medical School of Hannover, 30625, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Fallgatter+AJ%22">Fallgatter AJ</searchLink>; Department of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), University of Tübingen, 72076, Tübingen, Germany.; German Center for Mental Health (DZPG), Partner Site Tübingen, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Figge+C%22">Figge C</searchLink>; Karl-Jaspers Clinic, European Medical School Oldenburg-Groningen, 26160, Oldenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Heilbronner+M%22">Heilbronner M</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Jäger+M%22">Jäger M</searchLink>; Department of Psychiatry II, Ulm University, Bezirkskrankenhaus Günzburg, 89312, Günzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Juckel+G%22">Juckel G</searchLink>; Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, 44791, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Konrad+C%22">Konrad C</searchLink>; Department of Psychiatry and Psychotherapy, Agaplesion Diakonieklinikum, 27356, Rotenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Navarro-Flores+A%22">Navarro-Flores A</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kohshour+MO%22">Kohshour MO</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Department of Immunology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.<br /><searchLink fieldCode="AU" term="%22Reich-Erkelenz+D%22">Reich-Erkelenz D</searchLink>; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Reimer+J%22">Reimer J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.; 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Psychiatrieverbund Oldenburger Land gGmbH, Karl-Jaspers-Klinik, 26160, Bad Zwischenahn, Germany.<br /><searchLink fieldCode="AU" term="%22Schulze+TG%22">Schulze TG</searchLink>; German Center for Mental Health (DZPG), Partner site Munich-Augsburg, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Heilbronner+U%22">Heilbronner U</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Budde+M%22">Budde M</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Papiol+S%22">Papiol S</searchLink>; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, 80336, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Falkai+P%22">Falkai P</searchLink>; Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804, Munich, Germany.; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, 80336, Munich, Germany.; German Center for Mental Health (DZPG), Partner site Munich-Augsburg, Munich, Germany.
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