Foxs1-mediated transformation of CD34+ fibroblast to myCAFs promotes tumor growth.

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Title: Foxs1-mediated transformation of CD34+ fibroblast to myCAFs promotes tumor growth.
Authors: Yang J; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Faculty of Medical Laboratory Science, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Artificial Intelligence Medicine, Shanghai Academy of Experimental Medicine, Shanghai, China., Chen T; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Zhang R; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China., Xu J; Department of Pediatric Orthopedics, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao X; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Yang M; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China., Chen Z; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Sun S; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China., Chen X; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhang S; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Jiang L; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Zheng Y; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Hu Y; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Xu Q; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Lin W; State Key Laboratory for Oncogenes and Related Genes, Department of Cardiology, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. 21520@renji.com., Shen L; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn.; Faculty of Medical Laboratory Science, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn.; Institute of Artificial Intelligence Medicine, Shanghai Academy of Experimental Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn., Zhang L; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. li.zhang@shsmu.edu.cn.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jul 04. Date of Electronic Publication: 2026 Jul 04.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1757-4684
DOI:10.1038/s44321-026-00476-8