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Foxs1-mediated transformation of CD34+ fibroblast to myCAFs promotes tumor growth.

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Title: Foxs1-mediated transformation of CD34+ fibroblast to myCAFs promotes tumor growth.
Authors: Yang J; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Faculty of Medical Laboratory Science, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Artificial Intelligence Medicine, Shanghai Academy of Experimental Medicine, Shanghai, China., Chen T; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Zhang R; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China., Xu J; Department of Pediatric Orthopedics, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao X; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Yang M; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China., Chen Z; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Sun S; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China., Chen X; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhang S; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Jiang L; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Zheng Y; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Hu Y; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Xu Q; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Lin W; State Key Laboratory for Oncogenes and Related Genes, Department of Cardiology, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. 21520@renji.com., Shen L; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn.; Faculty of Medical Laboratory Science, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn.; Institute of Artificial Intelligence Medicine, Shanghai Academy of Experimental Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn., Zhang L; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. li.zhang@shsmu.edu.cn.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jul 04. Date of Electronic Publication: 2026 Jul 04.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Foxs1-mediated transformation of CD34<superscript>+</superscript> fibroblast to myCAFs promotes tumor growth.
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  Data: <searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Faculty of Medical Laboratory Science, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Artificial Intelligence Medicine, Shanghai Academy of Experimental Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+T%22">Chen T</searchLink>; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+R%22">Zhang R</searchLink>; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Department of Pediatric Orthopedics, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+S%22">Sun S</searchLink>; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Jiang+L%22">Jiang L</searchLink>; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+W%22">Lin W</searchLink>; State Key Laboratory for Oncogenes and Related Genes, Department of Cardiology, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. 21520@renji.com.<br /><searchLink fieldCode="AU" term="%22Shen+L%22">Shen L</searchLink>; Department of Laboratory Medicine, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn.; Faculty of Medical Laboratory Science, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn.; Institute of Artificial Intelligence Medicine, Shanghai Academy of Experimental Medicine, Shanghai, China. shenlisong@xinhuamed.com.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Cardiology and Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. li.zhang@shsmu.edu.cn.
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        Value: 10.1038/s44321-026-00476-8
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        Text: English
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      – TitleFull: Foxs1-mediated transformation of CD34+ fibroblast to myCAFs promotes tumor growth.
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              Text: 2026 Jul 04
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