Synergistic SGLT2 and GLP-1R targeting alleviates systemic inflammation-induced and M1 monocyte-driven endothelial dysfunction in coronary artery disease.
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| Title: | Synergistic SGLT2 and GLP-1R targeting alleviates systemic inflammation-induced and M1 monocyte-driven endothelial dysfunction in coronary artery disease. |
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| Authors: | Mroueh A; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France., Fakih W; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France., Kerth S; Experimental and Molecular Pediatric Cardiology, TUM University Hospital, German Heart Center Munich, Technical University Munich, Munich, Germany., Kikuchi S; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France.; Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.; Cardiology Department, Strasbourg University Hospital, 1 Place de L'Hôpital, 67000, Strasbourg, France., Aboueddahab C; Cardiology Department, Strasbourg University Hospital, 1 Place de L'Hôpital, 67000, Strasbourg, France., Gong DS; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France.; College of Pharmacy, Mokpo National University, 1666 Yeongsan-Ro, Cheonggye-Myeon, Muan-Gun, Jeonnam, 58554, Republic of Korea., Choi M; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France.; College of Pharmacy, Mokpo National University, 1666 Yeongsan-Ro, Cheonggye-Myeon, Muan-Gun, Jeonnam, 58554, Republic of Korea., Nicolas A; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France., Fass S; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France., Trimaille A; Cardiology Department, Strasbourg University Hospital, 1 Place de L'Hôpital, 67000, Strasbourg, France., Granier A; Cardiology Department, Strasbourg University Hospital, 1 Place de L'Hôpital, 67000, Strasbourg, France., Carmona A; Cardiology Department, Strasbourg University Hospital, 1 Place de L'Hôpital, 67000, Strasbourg, France., Amissi S; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France., Pompach P; Institute of Biotechnology, Czech Academy of Sciences, Vestec, Czech Republic., Oak MH; College of Pharmacy, Mokpo National University, 1666 Yeongsan-Ro, Cheonggye-Myeon, Muan-Gun, Jeonnam, 58554, Republic of Korea., Jesel L; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France.; Cardiology Department, Strasbourg University Hospital, 1 Place de L'Hôpital, 67000, Strasbourg, France., Görlach A; Experimental and Molecular Pediatric Cardiology, TUM University Hospital, German Heart Center Munich, Technical University Munich, Munich, Germany., Morel O; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France. olivier.morel@chru-strasbourg.fr.; Cardiology Department, Strasbourg University Hospital, 1 Place de L'Hôpital, 67000, Strasbourg, France. olivier.morel@chru-strasbourg.fr., Schini-Kerth V; FMTS, Biomedicine Research Center of Strasbourg, UR 3074, Translational Cardiovascular Medicine, University of Strasbourg, 1 Rue Eugène Boeckel, 67000, Strasbourg, France. valerie.schini-kerth@unistra.fr. |
| Source: | Cardiovascular diabetology [Cardiovasc Diabetol] 2026 Jul 04. Date of Electronic Publication: 2026 Jul 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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