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Cichorium intybus L. polysaccharide improves growth performance and colonic barrier function in weaned piglets via the microbiota-HDCA-TGR5-Akt-NF-κB signaling axis: validation by FMT and in vitro models.

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Title: Cichorium intybus L. polysaccharide improves growth performance and colonic barrier function in weaned piglets via the microbiota-HDCA-TGR5-Akt-NF-κB signaling axis: validation by FMT and in vitro models.
Authors: Cao L; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China., Zhang G; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Zhang G; College of Animal Science and Technology, Hebei Agricultural University, Baoding, China., Zhang F; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Li W; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Song Q; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., He J; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Zhao J; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Zhang Z; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. zeyuzhang07@cau.edu.cn.
Source: Journal of animal science and biotechnology [J Anim Sci Biotechnol] 2026 Jul 06; Vol. 17 (1). Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101581293 Publication Model: Electronic Cited Medium: Print ISSN: 1674-9782 (Print) Linking ISSN: 16749782 NLM ISO Abbreviation: J Anim Sci Biotechnol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Cichorium intybus L. polysaccharide improves growth performance and colonic barrier function in weaned piglets via the microbiota-HDCA-TGR5-Akt-NF-κB signaling axis: validation by FMT and in vitro models.
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  Data: <searchLink fieldCode="AU" term="%22Cao+L%22">Cao L</searchLink>; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; College of Animal Science and Technology, Hebei Agricultural University, Baoding, China.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22Song+Q%22">Song Q</searchLink>; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22He+J%22">He J</searchLink>; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. zeyuzhang07@cau.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101581293%22">Journal of animal science and biotechnology</searchLink> [J Anim Sci Biotechnol] 2026 Jul 06; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Jul 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101581293 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1674-9782 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216749782%22">16749782 </searchLink><i>NLM ISO Abbreviation: </i>J Anim Sci Biotechnol <i>Subsets: </i>PubMed not MEDLINE
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      – Type: doi
        Value: 10.1186/s40104-026-01449-0
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      – Code: eng
        Text: English
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      – TitleFull: Cichorium intybus L. polysaccharide improves growth performance and colonic barrier function in weaned piglets via the microbiota-HDCA-TGR5-Akt-NF-κB signaling axis: validation by FMT and in vitro models.
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              M: 07
              Text: 2026 Jul 06
              Type: published
              Y: 2026
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